AAMRA Allied Ayurveda Medical Research Abstracts

Abstract no :  4-1..4-DG-082 Author(s) :  Chattopadhyay, R.R Address :  (Biometry Research Unit, Indian Statistical Institute, 203 Barrackpore Trunk Road, Calcutta 700 035, WB, India) Source :  Journal of Ethnopharmacology, v. 67(3): p. 367-372, 1999 Title :  A COMPARATIVE EVALUATION OF SOME BLOOD SUGAR LOWERING AGENTS OF PLANT ORIGIN. Abstract :      A comparison of blood sugar lowering activity of four medicinal plants (Azadirachta indica (NIMBA), Gymnema sylvestre (MESHASRINGI), Catharanthus roseus (TRINA RASNA) and Ocimum sanctum (TULASI )) were carried out against normal and streptozotocin-induced diabetic rat models. The plant extracts decreased the blood sugar level in varying degrees. Blood sugar lowering unit (BLU) of activity of each leaf extract and tolbutamide was calculated by ED50 values. Statistical analysis revealed significant (P less than 0.05) variation among the treatments as well as doses with regard to their blood sugar...

Abstract no :  4-1..4-BK-006 Author(s) :  Dave, K.K.; De, S. Address :  (Pharmaceutical Chemistry Laboratory, Institute of P.G. Teaching and Research, Gujarat Ayurveda University, Jamnagar 361 008, Gujarat, India Source :  Journal of Research in Ayurveda and Siddha, v. 17(3-4): p. 180-188, 1996 Title :   ANALYTICAL STUDY OF TALISADYA CHUNRNA. Abstract :      The analytical data of TALISADYA CHURNA, an Ayurvedic formulation prepared from TWAK (Cinnamomum sp.) ELA (Elettaria cardamomum (ELA )), Pippali (Piper longum (PIPPALI)), Marica (Piper nigrum (MARICHA)), Sunthi (Zingiber officinale (AARDRAKA)), Talisa (Taxus baccata (TALISA)) Bambusa bambos and Sarkara (Sugar) has been presented. Thin layer chromatographic patterns have been evolved for identifying the presence of the herbal ingredients along with the general parameters like loss on drying, ash value, water and alcohol soluble extractives, volatile oil content, sugar and silica content e...

Abstract no :  4-1..4-BK-007 Author(s) :  Thaamma, A.; Radhika, L.G.; Saudamini, C Address :   (Drug Standardization Unit, Ayurveda College Unit, Poojappura, Thiruvananthapuram 695 012, Kerala, India) Source :  Journal of Research in Ayurveda and Siddha, v. 17(1-2): p. 98-104, 1996 Title :  STANDARDIZATION OF AN AYURVEDIC FORMULATION - VACA-LASUNADI (BILVA PATRA) TAILA Abstract :      Vacalasunadi Taila, commonly known as Bilvapatra Taila is a formulation of four single drugs, viz., Acorus calamus (VACHA). Curcuma longa (HARIDRA), Allium sativum (LASUNA) and Eagle marvelous in sesame oil. TLC methods were evolved for the detection of the ingredients in BILVAPATRA TAILA.

Abstract no :  4-1..4-BK-008 Author(s) :   Alam, M.M.; Saraswathy, V.N.; Venugopalan, T.N.; Prabhakaran, V.A.; Namboodiri, P.K.N.;~   Rao, B.R Address :   (Indian Institute of Pancakarma Cheruthuruthy679 531, Kerala, India) Source :   Journal of Research in Ayurveda and Siddha, v. 18(3-4): p. 147-154, 1997 Title :   PHYSICO-CHEMICAL CHANGES IN MURCHANA TAILA AND BALASVAGANDHALAKSADI TAILA ON ABHYANGA Abstract :      MURCHANA Taila and Balasvagandhalaksadi Tail were used for Abhyanga in hemiplegia, monoplegia and paraplegia patients. Observations were made on the incubated MURCHANA Taila and Balasvagandhalaksadi Taila and collected from patients’ body after completion of ABHYANGA. The incubated MURCHANA Taila showed an increase in acid value and a new spot in the TLC. The recovered MURCHANA TAILA and Balasvagandhalaksadi Taila from the body of patients showed changes in acid value, specification value, change in the shape of visible spec...

Abstract no :  4-1..4-BK-009 Author(s) :   Nair, R.B.; Pillai, R.P.; Nair, K.V.; Nair, A.R.; Nair, C.P.R.; Nalinakshan, A Address :   (Central Research Institute (Ay.), Road No.66, Punjabi Bagh, New Delhi 110026, India) Source :   Journal of Research in Ayurveda and Siddha, v. 19(1-2): p. 49-58, 1998 Title :  HEPATOPROTECTIVE EFFECT OF GUDAPIPPALI, VASAGULUCHYADI ARKORN, PATOLAKATUROHINYADI ARKORN, DRAKSHADI ARKORN AND MADANTHA DECOCTION ON RATS - A COMPARATIVE STUDY Abstract :      The effect of a few composite Ayurvedic preparations and a leaf decoction in reducing CC14 induced hepatic injury was studied in albino rats. Drug administration for 10 days could significantly reduce the elevated enzyme levels as well as reduce the wet liver weight. Various drugs tried were effective to varying degrees. Maximum reduction in serum and liver enzyme levels as well as serum bilirubin was brought about by PATOLAKATUROHINYADI ARKAM indicating its supe...

Abstract no :  4-1..4-BK-010 Author(s) :   Capasso, R.; lzzo, A.A.; Pinto, L.; Bifulco, T.; Vitobello, C.; Mascolo, N Address :   (Department of Pharmaceutical Sciences, Via Ponte Don Melillo, 84084 Fisciano\y Salerno, Italy) Source :   Fitoterapia, v. 71(Suppl.): p. S58-S65, 2000     Title :   PHYTOTHERAPY AND QUALITY OF HERBAL MEDICINES Abstract :       The extensive use of plants as medicines has pointed out that herbal medicines are not as safe as frequently claimed. Therefore, it can be harmful to take herbal medicines without being aware of their potential adverse effects. A comprehensive surveillance system for monitoring the adverse effects of herbal medicines is now essential. Also knowledge of the correlation existing between the marker compounds and other ingredients that occur in plants is a necessary requirement for ensuring the efficacy and quality of the herbal medicines.

Abstract no :  4-1..4-BK-011 Author(s) :   Chauhan, S.K.; Agrawal, S Address :   (R&D Centre, Indian Herbs, Saharanpur, UP, India) Source :  Indian Drugs, v. 36(6): p. 368-371, 1999 Title :  ACCELERATED STABILITY STUDIES OF A POLYHERBAL PREPARATION IN CAPSULE FORM Abstract :      The stability of the polyherbal capsule (containing Glycyrrhiza glabra (YASTI), Solanum xanthocarpum (SVETA KANTAKARI), Albizia lebbeck, Alpinia galanga (MAHABARIVACHA ), Sida cordifolia (BALA), Hedychium spicatum (SATI). Piper longum (PIPPALI), Saussurea lappa (KUSTA ), Zingiber officinale (AARDRAKA) and Ocimum sanctum (TULASI )) by exposing it to elevated conditions of temperature i.e. 45 degree C and 40 degree C with 75 percent relative humidity was studied. The samples periodically analyzed up to six months for their organoleptic characteristics, assay of few plant ingredients and the HPTLC finger printing and their peak area analysis, were found to be stabl...

Abstract no :  4-1..4-BK-012 Author(s) :  Sood, R.P Address :   (Institute of Himalayan Bio-resource Technology (CSIR), Palampur, HP, India) Source :   National Seminar on Drugs from Himalayan Herbs : Present Status & Future Strategies, Kumaun University, Nainital, India, p. 17-18, March 26-28, 1999 .   Title :  DRUG MATERIALS OF HIMALAYAN ORIGIN Abstract :        A variety of herbal shrubs and trees grow under the environment of great Himalayas. Seven out of top ten medicinal plants of the world have their origin in the Himalayas. Statistical data show that a total turnover of Indian herbal drugs in 1997 was of the order of Rs.2300 crores, which is expected to increase to Rs.4000 crores by the end of this century. The export of herbal drugs in 1997 was only of the tune of Rs.255 crores, which implies the people of greater utility of drug material within the country. The present status and future strategies of some important me...

Abstract no :  4-1..4-BK-013 Author(s) :  Gharpure, Y.H Address :   (Gharpure Group, Mumbai Maharashtra, India) Source :   Eastern Pharmacist, v. 42(496): p. 43-45, 1999 Title :   TECHNOLOGY EXPORT Abstract :            Indian technologies for bulk drugs are at par and ever superior to the technologies elsewhere in the world and India has good potential to market its technological strength to a large number of countries. Export of major bulk drugs from India (menthol at the top of the list) during 1996-97, some of the major branded drugs coming off patent during 1977 -2000 (including paclitaxel), milestones in medicine (from Ayurveda to Western medicine), and shave of Ayurvedic drugs in Europe have been presented in four tables.

Abstract no :  4-1..4-BK-014 Author(s) :  Artiges, A Address :   (Council of Europe, European Department for the Quality of Medicines, 226 Avenue de Colmar, F-67029 Strasbourg Cedex I, France) Source :   Herba Polonica, v. 45(4): p. 288-289, 1999 (Pol; Eng) Title :   PHARMACOPOEIAL STANDARDS FOR HERBAL MEDICINAL PRODUCTS IN EUROPE Abstract :           Raw material and herbal medicines in the up-to-date European Pharmacopoeia and the tasks for the pharmacopoeia commission on this field, because the extension of monographs in edition "2000" compared to "1997" means forty two new herbal products have been reported. There will be new monographs dealing with galenic forms and quality control methods in the edition PhE 2000.

Abstract no :  4-1..4-BK-015 Author(s) :  Kabelitz, L Address :   (Phytolab GmbH and Company, K.G., Dutendorfer Str.5-7, D-91487 Vestenbergsgreuth, Deutschland) Source :   Herba Polonica, v. 45(4): p. 299-301, 1999 (Pol; Eng).   Title :   QUALITY REQUIREMENTS FOR HERBAL MEDICINAL PRODUCTS Abstract :        The quality requirements for herbal medicinal products concern growing and harvest of plant material, drying conditions, the use of pesticides - determined by GAP. For herbal medicines there are GMP directives, extended by the data concerning "active pharmaceutical substances". The raw material, preparations and finished products must have a specification to assure the reproduction of quality, but the methods of specification and control should take into consideration the PhE data. The stability control of active substances and finished products should be conducted according to valid directives. 

Abstract no :  4-1..4-BK-016 Author(s) :  Muzaffer Alam; Saraswathy, V.N.; Venugopalan, T.N.; Jaya, N.; Namboodiri, P.K.N Address :   (Research Officer, Indian Institute of Pancha Karma, Cheruthuruthy 679 531, Kerala, India) Source :  Bulletin of Medico-Ethnobotanical Research, v. 19(1-2): p. 71-75, 1998.   Title :  COMPARATIVE ANALYTICAL STUDIES ON BRHAT MASA TAILA. Abstract :       BRHAT MASA TAILA was prepared as per the textual method and by modified method in which CHAGA MAMSA (flesh of goat) was deleted from the formulation. Both types of preparations were compared for pharmacopoeial parameters, visible light spectrum and thin-layer chromatography. The acid value and saponification value were 6.43, 219.68 and 6.9, 203 in the textual and modified methods respectively. The visible light spectrum showed difference in the shape at the wave length 460 nm to 550 nm. The thin layer chromatography did not show any difference in either typ...

Abstract no :  4-1..4-BK-017 Author(s) :  Czerny, M.; Grosch, W Address :   (Deutsche Forschungsanstalt fur Lebensmittelchemie, Lichtenbergstrasse 4, D 85 748 Garching, Germany) Source :   Journal of Agricultural and Food Chemistry, v. 48(3): p. 868-872, 2000   Title :  POTENT ODORANTS OF RAW ARABICA COFFEE. THEIR CHANGES DURING ROASTING Abstract :         Aroma extract dilution analysis of raw Arabica coffee (Coffea arabica (KAAFI)) revealed 3-isobutyl-2-methoxypyrazine, 2-methoxy-3,5-dimethylpyrazine (II), ethyl 2-methylbutyrate (III), ethyl 3-methylbutyrate (IV), and 3-isopropyl-2-methoxypyrazine (V) as potent odorants. The highest odor activity value was found for I followed by II, IV, and V. It was concluded that I was responsible for the characteristic, peasy odor note of raw coffee. Twelve odorants occurring in raw coffee and (E)-beta-damascenone were also quantified after roasting. The concentration of I did not change, whe...

Abstract no :  4-1..4-BK-018 Author(s) :  de Ancos, B.; lbanez, E.; Reglero, G.; Cano, M.P Address :   (Department of Plant Foods Science and Technology, Institute del Frio, CSIC, Ciudad Universitaria s/n, 28040 Madrid, Spain) Source :   Journal of Agricultural and Food Chemistry, v. 48(3): p. 873-879, 2000 Title :   FROZEN STORAGE EFFECTS ON ANTHOCYANINS AND VOLATILE COMPOUNDS OF RASPBERRY FRUIT Abstract :           The quantitative and qualitative evolution of the anthocyanins and volatile compounds of four raspberry cultivars growing in Spain were analyzed raw, just frozen, and during long-term frozen storage at -20 degree C for a I year period. HS-SPME coupled with GC-MS and HPLC techniques were employed to study the evolution of the volatile compounds and the individual anthocyanins, respectively. The volatile aroma composition changes produced by the freezing process and long-term frozen storage were minimal. Only a significa...

Abstract no :  4-1..4-BK-019 Author(s) :  Santhosh, V.; Rajkumar, G.; Anilkumar, E.S.; Rajasekharan, S.; Pushpangadan, P Address :   (Tropical Botanic Garden and Research Institute, Palode, Thiruvananthapuram 695 562, Kerala, India) Source :   Bulletin of Medico-Ethno botanical Research, v. 19(3-4): p. 119-134, 1998 Title :  MARKET VALUE OF MEDICINAL PLANT WEALTH: A CASE STUDY OF COLLELCTION AND MARKETING IN SOUTHERN DISTRICTS OF KERALA Abstract :          Due to the current revival of interest in herbal drugs and pharmaceuticals, there has been increasing demand for medicinal plants from the forest leading to over exploitation causing depletion or even extinction of many rare medicinal plant species. The present communication highlights the collection and marketing of 151 important medicinal plants which are most commonly used in pharmaceuticals, traditional system of medicine like Ayurveda. Siddha as well as in other local health...

Abstract no :  4-1..4-BK-020 Author(s) :  Bartley, J.P.; Jacobs, A.L Address :   (School of Physical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, Australia) Source :  Journal of the Science of Food and Agriculture, v. 80(2): p. 209-215, 2000 Title :  EFFECTS OF DRYING ON FLAVOR COMPOUNDS IN AUSTRALIAN-GROWN GINGER (ZINGIBER OFFICINALE). Abstract :         The volatile compounds responsible for the flavor of Australian-grown ginger have been extracted using supercritical carbon dioxide. Both fresh and dried ginger samples have been examined and the major effects of the drying process are a reduction in gingerol content, an increase in terpene hydrocarbons and the conversion of some monoterpene alcohols to their corresponding acetates.

Abstract no :  4-1..4-BK-021 Author(s) :   Rovio, S.; Hartonen, K.; Holm, Y.; Hiltunen, R.; Riekkola, M.L. Address :  (Laboratory of Analytical Chemistry, Department of Chemistry, PO Box 55, FIN 00014 University of Helsinki, Finland) Source :   Flavour and Fragrance Journal, v. 14(6): p. 399-404, 1999 Title :     EXTRACTION OF CLOVE USING PRESSURIZED HOT WATER Abstract :         Sub critical water extraction was used to extract eugenol and eugenyl acetate from clove at various temperatures and pressures where water was in either the liquid or gas (steam) phase. Several solid phase materials were tested in order to quantitatively and selectively collect the analytes after the water extraction. The extraction kinetics with sub critical water was very fast at high temperatures, giving a 100 percent recovery after 15 min for eugenol and eugenyl acetate. Both eugenol and eugenyl acetate were found to be stable at the highest extraction ...

Abstract no :  4-1..4-BK-022 Author(s) :  Agarawal, S.;Sharma,R.K Address :   (All India Coordinated Spices Improvement Project, SKN College of Agriculture, Rajasthan Agricultural University, Jobner 303 329, Rajasthan, India) Source :   Indian Journal of Areca nut, Spices and Medicinal Plants, v. 1(2): p. 63-64, 1999   Title :  EFFECT OF STORAGE OF SEEDS OF FENNEL, CORIANDER AND CORIANDER POWDER ON QUALITY Abstract :       The seeds of fennel (Foeniculum vulgare (MISREYA)), coriander {Coriandrum sativum (DHANYAKA)) and coriander powder were stored in different packing bags viz. cotton bag, polythene bags, paper bag or aluminium foil bags to study the loss of volatile oil contents with time. Fennel seeds could be stored in polythene bags or cotton bags for one year without much loss of volatile oil contents. However, coriander seeds could be stored for six months only. The best storage material for ground coriander was found to be alumin...

Abstract no :  4-1..4-BK-023 Author(s) :  Satyanarayana, V.V.; Sukumaran, C.R Address :   (College of Agricultural Engineering, Bapatla 522 101, AP, India) Source :   Andhra Agricultural Journal, v. 46(3&4): p. 229-233, 1999 Title :   ON FARM TECHNOLOGY OF TURMERIC PROCESSING AND SUGGESTIONS FOR MECHANIZATION Abstract :           Turmeric (Curcuma longa (HARIDRA)) is an important spice crop with many diversified uses. Processing of turmeric rhizomes freshly dug out of the earth is essential both for the development of an attractive color, characteristic aroma and good commercial value. Processing technology adopted in Duggirala area of Guntur district has been presented with a view to explore the possibilities for mechanizing and improving the processing techniques. Various unit operations involved in turmeric processing presently carried out manually can be mechanized by adopting related processing machinery such as turmeric b...

Abstract no :  4-1..4-BK-024 Author(s) :   Agarwal, S.; Singh, R.H Address :   (Department of Kayachikitsa, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, UP, India) Source :  Proceedings of International Congress on "Ayurveda-2000", Chennai, TN, India, p. 221, January 28-30,2000   Title :   STANDARDIZATION, QUALITY CONTROL AND QUALITY ASSURANCE OF AYURVEDIC FORMULATIONS : AN OVERVIEW. Abstract :        Paper covers the details of how to achieve quality control and standardization of natural products which is essentially a three tier scientific and industrial activity involving. 1. Standardization of raw materials, 2. Standardization of process technology and 3. Standardization of finished products, besides testing of therapeutic efficacy and toxicity profile. The detailed strategy has been presented.

Abstract no :  4-1..4-BK-025 Author(s) :  Dwivedi, P.K.; Pandey, S.; Jha, C.B Address :   (Department of Rasa Shastra, IMS., Banaras Hindu University, Varanasi, UP, India) Source :   Sachitra Ayurveda, v. 51(7): p. 541-543, 1999 Title :  TECHNIQUES FOR AYURVEDIC DRUG PREPARATION AND STANDARDIZATION Abstract :           Products in classified way, are included in this article and their pharmaceutical/manufacturing techniques, control parameters, individually applicable, appliances-instruments etc. used, self-life of the products and their therapeutic uses, have been elaborately discussed. Role of standardization of raw material, process and products, is also indicated.

Abstract no :  4-1..4-BK-026 Author(s) :   Kamalapurkar, V.O.; Kamalapurkar, O.S.; Raju, S.A Address :   (Department of Pharmacognosy, HKE's College of Pharmacy, Gulbarga585 105, Karnataka, India) Source :   Proceedings of International Congress on "Ayurveda2000", Chennai, TN, India, p. 228-229, January 28-30,2000   Title :   QUALITY CONTROL OF ASHWAGANDHA IN AYURVEDIC FORMULATIONS Abstract :        Ashwagandha (Withania somnifera (ASVAGANDHA)) is used in various Ayurvedic formulations for the treatment of rheumatism, gout, hypertension, nervine and skin diseases. It is a strength and vigor-promoting drug. A method is proposed for its quality control in Ayurvedic formulations. 100 mg of the powdered, dried crude drug was extracted with 25 ml of acetone-pet, ether solvent mixture (1:1) in soxhiet extractor at 60-70 degree C. The extract was evaporated on water bath. The residue is dissolved in ethanol (95 percent) and the volume is ...

Abstract no :  4-1..4-BK-027 Author(s) :   Nair, K.V.; Nesamany, S Address :   (Regional Research Institute (Drug Research), CCRAS, Poojapura, Trivandrum 695 012, Kerala, India) Source :   Proceedings of International Congress on "Ayiirveda-2000", Chennai, TN, India, p. 222-223, January 28-30,2000   Title :  GUIDELINES FOR COLLECTION, STORAGE AND EXPIRY PERIOD FOR AYURVEDIC DRUGS/MEDICINES Abstract :       Ayurveda has its own code of standards for drugs/medicines. In their code, proper collection method of crude drugs, their preservation and expiry period of different medicines such as KASHAYA, CHURNA, GHEE, AVALEHA etc are well documented. Moreover, the modern technology gives us a few more methods to adopt. An attempt to review all these aspects with a desire to make the subject more informative and adoptable has been dealt with.

Abstract no :  4-1..4-BK-028 Author(s) :   Ojha, J.K Address :   (Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, UP, India) Source :   Proceedings of International Congress on "Ayurveda-2000", Chennai, TN, India, p. 69, 28-30 January,   Title :   APPLIED AYURVEDIC PRINCIPLES IN THE FORMULATION OF PROPRIETARY MEDICINE Abstract :       The fundamentals of Ayurveda for the preparation of proprietary medicine are based on the following factors: Principal and main drug used in the combination; helping and associate drugs to help the main drug; balancing drugs to keep balance over dosha and dhatu and other factors of the body in order to make it a holistic preparation; preservative drugs. The principles have been exemplified by Chyavanprash where Emblica officinalis (AAMALAKI) is the main drug and 34 other drugs including DASHAMUL, ASHTAVARGA, etc; are helping and associate drugs to help main d...

Abstract no :  4-1..4-BK-029 Author(s) :  Padiyar, U.A.; Duggal, R.K.; Brindavanam, N.B.; Narayana, D.B.A Address :  (Dabur Research Foundation, 22 Site IV, Sahibabad 201 012, UP, India) Source :   Proceedings of International Congress on "Ayurveda-2000", Chennai, TN, India, p. 225-226, January 28-30, 2000     Title :  ASSESSMENT OF PRODUCT STABILITY FOR AYURVEDIC FORMULATIONS CASE STUDIES USING PHYSICO-CHEMICAL PROTOCOLS Abstract :       An attempt to evaluate product stability for one CHURNA and its correlating tablet dosage form, a proprietary syrup formulation and a topical formulation based on Ayurveda has been dealt with. Accelerated stability conditions were adopted as per ICH guidelines. Physicochemical protocols including identification and quantification of markers were employed to analyze these samples at prescribed time intervals. The observations of above accelerated stability studies for above four formulations will b...

Abstract no :  4-1..4-BK-030 Author(s) :  Satakopan, S Address :   (Food and Drugs Laboratory, Vadodara, Gujarat, India) Source :  Indian Drugs, v. 37(2): p. 1 14-118, 2000 Title :  QUALITY CONTROL FOR AYURVEDIC, SIDDHA AND UNANI DRUGS - ATTITUDES AND APPROACHES. Abstract :         Need of skill for drafting of monographs, standardization of classical drugs, quality control, identification, purity and strength of classical drugs before marketing of Ayurvedic, Unani and Siddha drugs has been emphasized.

Abstract no :  4-1..4-BK-031 Author(s) :  Saxena, R.B Address :   (Indian Institute of Ayurveda for Drug Research Central Council for Research in Ayurveda & Siddha, Tarikhet 263 663, UP, India) Source :  Sachitra Ayurveda, v. 51(9): p. 692-695,  1999 Title :   STUDY OF NEUTRAL OIL CONTENT AND MEDICINAL VALUES OF MURCHHITA TILA OIL Abstract :         Neutral oil content, medicinal and refractive index values have been determined from different equations and compared with the experimental values of crude TILA (Sesamum indicum (TILA) oil) and MURCHHITA TIL oil. These comparative values are very useful to maintain uniformity  and quality of MURUCHHITA TILA oil.

Abstract no :  4-1..4-BK-032 Author(s) :  Sheth, N.R.; Joshi, D.M.; Chauhan, M.G.; Bhavsar, G.C.; Patel, K.N Address :   (B. K. Mody Government Pharmacy College, Polytechnic Campus, Rajkot 360 003, Gujarat, India) Source :   Proceedings of International Congress on "Ayurveda-2000", Chennai, TN, India, p. 228, January 28-30, 2000 Title :  STANDARDIZATION OF TRIKATU CHURNA Abstract :         TRIKATU CHURNA is the fine powder mixture of fruit of Piper longum (PIPPALI), fruit of Piper nigrum (MARICHA) and rhizome of Zingiber officinale (AARDRAKA) in equal proportion. All the individual ingredients were first examined thoroughly for their authenticity and purity. These ingredients were then powdered, mixed together and labelled as self prepared 'TRIKATU CHURNA'. Market samples of TRIKATU CHURNA were also collected, evaluated and was compared with that of self prepared CHURNA. It was evaluated by powder microscopy, preliminary phytochemical s...

Abstract no :  4-1..4-BK-033 Author(s) :   Singh, D.K.; Singh, R.A Address :   (Research and Development Centre, 6/14 Kirti Nagar Industrial Area, New Delhi 110 015, India) Source :   Proceedings of International Congress on "Ayurveda-2000", Chennai, TN, India, p. 231, January 28-30, 2000 Title :   FINGERPRINTING OF GUGGULU (COMMIPHORA WIGHTII) AND ITS MAJOR AYURVEDIC FORMULATION (TRIPHALA, GOKSURADI AND MAYAYOGRAJ GUGGULU) WITH HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY Abstract :          HPTLC Fingerprints of guggulu and three Ayurvedic formulations containing guggulu has been compared. Guggulu (Commiphora wightii (GUGGULU)) contains essential oil, gum, resin and steroids, which has medicinal value in number of Ayurvedic formulation. Fingerprinting of guggulu herb has been compared with the fingerprints of aprox.40 herbal drugs extracted in methanol and using the same mobile phase.

Abstract no :  4-1..4-BK-034 Author(s) :  Satish Kumar Address :  (Department of Rasasasthra, Institute of Medical Science, Banaras Hindu University, Varanasi 221 005, UP, India) Source :    Proceedings  of International Congress  on "Ayurveda-2000", Chennai, TN, India, p. 124-125, 28-30 January, 2000 Title :  KSHAR SUTRA IN ANCIENT CLASSICS. Abstract :          To find out a suitable drug which can replace SNUHI latex for the preparation of Kshar-Sutra, various agents like KALKA of Ghrita Kumari, Gum acacia, Gandhaviroja, udumbar, Amaltas, Guggulu etc. were tried. None of them were found suitable to replace SNUHI latex in terms of quality of thread and efficacy. So it is necessary to find out a suitable agent which can replace the use of Snuhi latex in the preparation of Kshar Sutra. The advantages & disadvantages of various types of Kshar Sutra have been discussed.

Abstract no :  4-1..4-BK-035 Author(s) :   Narayana, D.B Address :   (Dabur Research Foundation, 22 Site-IV, Sahibabad 201 010, UP, India) Source :  Proceedings of International Congress on "Ayurveda-2000", Chennai, TN, India, p. 6768, 28-30 January, 2000 .   Title :  ANALYTICAL STANDARDIZATION OF HERBAL FORMULATIONS : CHEMICAL & INSTRUMENTAL TECHNIQUES. Abstract :       The objective of quality protocol development activities should be to ensure a 'minimum' therapeutic guarantee' to the user. Such objective can be accomplished by ensuring a fairly consistent quality in the raw materials, a validated process control system and adequate checks on the finished products. In order to ensure the chemical sanctity of crude herbs, extracts and finished production, the present approaches can be classified under the following categories: i) Physico-chemical Analysis; ii) estimation of functional groups; iii) quantifications of marketers and ...

Abstract no :  4-1..4-BK-036 Author(s) :   Patel, K.N.; Shah, U.D.; Patel, H.D.; Shah B.K Address :   (Department of Pharmacognosy, L.M. College of Pharmacy, Ahmedabad, Gujarat, India) Source :   Proceedings of International Congress on "Ayurveda-2000", Chennai, TN, India, p. 188-189, 28-30 January 2000 Title :  HPTLC METHOD FOR ESTIMATION OF PHYLLANTHIN IN PHYLLANTHUS AMARUS AND ITS MARKET POLYHERBAL FORMULATIONS Abstract :        A precise, simple and reproducible HPTLC method for the determination of phyllanthin in Phyllanthus amarus and its market polyherbal formulations was developed using tolueneethylacetate (4:2 V/V) as mobile phase and scanned at 280 nm. The sensitivity found for HPTLC was 50 ng and linearity was observed in the range of 200-10000 ng. The leaf contain maximum amount of phyllanthin (0.5449 percent) followed by herb (0.485 percent), stem (0.013 percent) and root (0.0049 percent). The market formulations were evalu...

Abstract no :  4-1..4-BK-037 Author(s) :   Sarashwathi, A Address :   (Captain Srinivasa Murti Drug Research Institute for Ayurveda (CCRAS), Arumbakkam, Chennai 600 106, TN, India) Source :   Proceedings of International Congress on "Ayurveda-2000", Chennai, TN, India, p. 224, January 28-30, 2000 Title :   DEVELOPMENT OF HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHIC FINGER PRINTS FOR AYURVEDIC DRUGS - A SELECT STUDY Abstract :            The paper deals with the quality assessment of certain plants and herbal medicines using HPTLC besides physicochemical standards. The parameters evolved can be used to lay down pharmacopoeial standards for these drugs.

Abstract no :  4-1..4-BK-038 Author(s) :  Shanmugasundaram, P Address :   (C.L.Baid Mehta College of Pharmacy, Chennai 600 096, TN, India) Source :   Proceedings of International Congress on "Ayurveda2000", Chennai, TN, India, p. 75, 28-30 January, 2000 . Title :   ANALYTICAL EVALUATION OF PROPRIETARY AYURVEDIC COUGH SYRUPS Abstract :          Five market samples of cough syrups were taken for the qualitative physical and chemical analysis. An audit was also done to find out the common ingredients present in the preparations. Chemical analysis for alkaloids, tannins, phenols, flavanoids, saponins, natural steroids, sugars, proteins was carried out with prescribed test methods. The present study showed the market samples do not contain synthetic steroids antihistamines and narcotics. The qualitative analysis showed various phytochemicals at varying concentrations.

Abstract no :  4-1..4-BK-039 Author(s) :   Khiyani, R.M Address :   (Rasasasthra Shaskiye Ayurveda Mahavidyalaya, Nagpur, Maharashtra, India) Source :   SachitraAyurved, v. 50(12): p. 812-815, 1998 Title :  AYURVEDIC PREPARATIONS OF GUGGUL AND THEIR PROPERTIES Abstract :           Morphology, storage/properties, chemical constituents of guggul have been reported. Methods of preparing guggul formulations have been given. Its 91 formulation have been enumerated. Its dietary foods and side effects have also been mentioned.

Abstract no :  4-1..4-BK-040 Author(s) :  Padiyar, U.A.; Duggal, R.K.; Brindavanam, N.; Narayana, D.B.A Address :   (Dabur Research Foundation, 22 Site IV, Sahibabad 201010, UP, India) Source :   Proceedings of International Congress on "Ayurveda-2000", Chennai, TN, India, p. 224225, January 28-30, 2000 . Title :   ANCIENT APPROACHES TO QUALITY AND GOOD MANUFACTURING PRACTICES FOR AYURVEDIC MEDICINES : AN OVERVIEW Abstract :          Ancient Ayurvedic and medieval literature suggests that quality and manufacturing systems have been an integral part of ancient concepts related to pharmaceutics. While the industry is standing at a threshold of new initiatives in this direction, various citations spread in Ayurvedic literature related to quality and manufacturing practices for Ayurvedic formulations. This may help the industry to go a long way to maintain the fundamental spirit of Ayurveda, while changing the systems in time with mode...

Abstract no :  4-1..4-BK-041 Author(s) :  Lucas, D.P.S.K Address :   (Lucas II 324, Vi, Main 2nd Cross, Vijayanagar, Bangalore 500 040, Karnataka, India) Source :  Proceedings of International Congress on "Ayurveda-2000", Chennai, TN, India, p. 226, January 28-30, 2000 .   Title :  HINGU-EVALUATION OF MARKET SAMPLES. Abstract :       An effort is made to evaluate the genuinity in the market and a guideline has been given for selection of standard Hingu.

Abstract no :  4-1..4-BK-042 Author(s) :  Krishnamurthy, R.; Malve, K.K.; Shinde,B.M Address :  ( Forensic Science Laboratory, Kalina, Santacruz (E),Mumbai 400 098, Maharashtra, India) Source :  Journal of the Indian Academy Of forensic sciences, v. M(I&II.): p. 48-33, lvw Title :  LEGISLATIVE REQUIREMENTS PERTAINING TO QUANTIFICATION OF HEROIN AND OTHER DRUGS E.G. OPIUM AND CANNABIS ETC Abstract :      Brown sugar, the most widely abused drug is derived from opium extract or crude morphine. It contains heroin along with other opium alkaloids. Several chromatographic procedures have been described for the analysis of heroinin illicit preparations. Capillary g.c has proved to be a valuable tool for the analysis of the complex mixture. The high efficiency of the fused silica capillary column results in the tall narrow peaks which reduces determination limits. The larger variation in percentage of active ingredient of narcotic drugs is attr...

Abstract no :  4-1..4-BK-043 Author(s) :  Yen, G.C.; Chuang, D.Y Address :  (Department of food Science, National Chung Hsing University, 250 Kuokuang Road, Taichung 40 227, Taiwan, Republic of China) Source :  Journal of Agricultural and Food Chemistry, v. 48(7): p. 2760-2765, 2000 Title :  ANTIOXIDANT PROPERTIES OF WATER EXTRACTS FROM CASSIA TORA L. IN RELATION TO THE DEGREE OF ROASTING Abstract :      The antioxidant properties of water extracts from Cassia tora (CHAKRAMARDA) (WECTT), prepared under different degrees of roasting were investigated. The water extracts of unroasted Cassia tora (CHAKRAMARDA) (WEUCT) showed 94 percent inhibition of peroxidation of linoleic acid at a dose of 0.2 mg/mL, which was higher than that of alpha tocopherol (82 percent). Water extracts prepared from Cassia tora (CHAKRAMARDA) roasted at 175 degree C for 5 min and at 200 degree C for 5 min exhibited 83 percent and 82 percent, respectively, inhibition of l...

Abstract no :  4-1..4-BP-044 Author(s) :   Klepser, T.B.; Doucette, W.R.; Horton, M.R.; Buys, L.M.; Ernst, M.E.; Hoehns, J.D.; Kautzman,H.A.; Logemann, C.D.; Swegle, J.M.; Ritho, M. et.al. Address :   (University of  Iowa, Iowa City, IA, USA) Source :  Pharmacotherapy(ACCP Annual Meeting Abstracts, Oct. 24-27. 1999, Missouri, USA), v. 19(10): p. 1204, 1999 Title :  SURVEY OF HERBAL THERAPIES USAGE AND PATIENTS BELIEFS Abstract :      A survey was distributed to two random samples; patients attending eight family care clinics and residents within the state (random mailing). Thirteen hundred surveys were distributed; 100 in each clinic and 500 mailings. Data were categorized according to respondent herb use and data from these groups were compared. Seven hundred ninety four surveys were completed (61%) with 42% of respondents reporting herbal use. Commonly used products were (descending order) aloe, ginseng, Echinacea and St. John's wort....

Abstract no :  4-1..4-BP-045 Author(s) :   Lacy, M.K.; Metcalf, S.A.; Reward, P.A.;Webb, M.J.; Backes, J.M.; Blaine, P.J. Address :   (University of Kansas Medical Center, Kansas City, KS, USA) Source :   Pharmacotherapy (ACCP Annual Meeting Abstracts, Oct. 24-27, 1999, Missouri, USA), v. 19(10): p.1204, 1999 Title :  VITAMIN SUPPLEMENTATION AND NATURAL OR HERBAL PRODUCT UTILIZATION AMONG AMBULATORY CLINIC PATIENTS AT A UNIVERSITY MEDICAL CENTER Abstract :      Of 634 surveys distributed to clinic patients, 315 were returned for a response rate of 50 percent. Respondents were well matched for gender (52 percent female, 48 percent male), 46 percent were greater than 61 years old, and 58percent indicated current use of a vitamin/mineral and/or natural/herbal product. Most products listed by patients were vitamin/mineral supplements (69 percent, 352/511).Regarding natural/herbal therapy, 24 percent (87/357) of patients indicated current use of ...

Abstract no :  4-1..4-BP-046 Author(s) :  Kemper, F. Address :  (Unweltprobenbank fur Human Organprobenmit Datenbank der Westfalischen Wilhelms-Universitat, Domagkstr.ll, 48129, Munster, Deutschland) Source :   Herba Polonica, v. 45(4): p. 294-295, 1999 Title :  IMPORTANCE OF  PHYTOTHERAPY IN EUROPE. Abstract :      The article deals with: harmonizing terminology of herbal medicines, developing clear definition of phyto-medicines and developing European monographs for herbal raw material together with existing monographs, efficacy and safety of raw material and herbal medicines for the authorization procedure.

Abstract no :  4-1..4-BP-047 Author(s) :   Sharma, J.R. Address :   (Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow 226 015, UP, India) Source :  Journal of Medicinal and Aromatic Plant Sciences, v. 21(4): p.llll-1118, 1999 Title :   PGR ISSUES: NATIONAL CONCERN AND GLOBAL CONFLICTS WITH SPECIAL REFERENCE TO MEDICINAL AND AROMATIC PLANTS. Abstract :           Three factors have caused unprecedented national crisis of genetic erosion of MAP genetic resources: (i) bio-plundering and over-exploitation of wild resources leading to drug imperialism, (ii) unplanned destruction of natural habitat, and (iii) biopiracy through biotechnology under the umbrella of TRIPs of WTO. This has raised several PGR related issues which need for a clear national policy/strategy on PGR in general, and MAPs in particular. In-situ and ex-situ conservation of PGR, preservation of local wisdom/knowledge and traditions and protection of r...

Abstract no :  4-1..4-BP-048 Author(s) :   Keshavamurthy, K.R.; Shantha, T.R.; Vijayalakshmi, B. Address :  (Regional Research Centre (Ay.), Jayanagar, Bangalore 560 Oil, Karnataka, India) Source :   Proceedings of International Congress on "Ayurveda-2000", Chennai, TN, India, 159, 28-30 January 2000. Title :  CONTRIBUTION OF  KARNATAKA MEDICINAL PLANTS TO AYURVEDA IN THE MANAGEMENT OF SKIN DISEASES (KUSTA). Abstract :      Ayurveda in its classics in general and Caraka samhita in particular has reference to many plants which could be used for alleviating different types of skin diseases (KUSTA). Caraka samhita has a mention of 124 species belonging to 109 genera and 57 families of which 97 species belonging to 89 genera and 49 families occur in Karnataka State. Data on plants used in treating skin disorders in general and Karnataka in particular have been provided. The Sanskrit names, updated botanical names and local names are mention...

Abstract no :  4-1..4-BP-049 Author(s) :  Mitra, J. Address :  (Gujarat Ayurveda University, Jamnagar, Gujarat, India) Source :  Sachitra Ayurveda, v. 51(8): p. 606-613, 1999 (Eng; 2 ref). Title :   IMPORTANCE OF MEDICINAL PLANTS MENTIONED IN BUDDHIST LITERATURE. Abstract :       The works of Hinayana and Mahayana Schools of Buddhism have enumerated nearly 350 medicinal plants and classified them into various groups along with their component parts on the pattern of Caraka Samhita. A list of medicinal plants (313 only) has been furnished in Devanagri alphabetical order without botanical names. The letters H and M denotes their source from the works of Hinayana and Mahayana, respectively.

Abstract no :  4-1..4-BP-050 Author(s) :  Pandey, P.S.; Pandey, K.K. Address :  (Banaras Hindu University, Varanasi 221 005, UP, India) Source :  . Sachitra Ayurveda, v. 50(8): P. 588-591, 1998 Title :  ANALGESIC HERBAL EXTRACTS: A PRELIMINARY STUDY Abstract :      Analgesic herbal extracts mentioned in Caraka samhita (Chapter 4) was examined. 10 Plants useful in different kinds of body pains have been mentioned. Their botanical and English names, morphology, flowering time, occurrence, Ayurvedic properties, parts used and medicinal uses have been given. These plants can be used as single remedy or in combination to cure body aches.

Abstract no :  4-1..4-DG-051 Author(s) :  Gil, M.I.; Tomas Barberan, F.A.; Hess-Perce, B.; Holcroft, D.M.; Kader, A.A Address :  (Department of Pomology, University of California, Davis, California, 95616, USA) Source :  Journal of Agricultural and Food Chemistry, v. 48 (10): p. 4581-4589, 2000 Title :  ANTIOXIDANT ACTIVITY OF POMEGRANATE JUICE AND ITS RELATIONSHIP WITH PHENOLIC COMPOSITION AND PROCESSING Abstract :      Commercial pomegranate (DADIMA) juices showed an antioxidant activity (18-20 TEAC) three times higher than those of red wine and green tea (6-8 TEAC). The activity was higher in commercial juices extracted from whole pomegranates than in experimental juices obtained from the arils only (12-14 TEAC). HPLC-DAD and HPLC-MS analyses of the juices revealed that commercial juices contained the pomegranate tannin punicalagin (1500-1900 mg/L) while only traces of tBT~comp5ilncr were detected in the experimental juice obtained from a...

Abstract no :  4-1..4-DG-052 Author(s) :  Iwang, J.K.; Kong, T.W.; Back, N.I.; Pyun, Y. R Address :  (Department of Biomaterials Science and Engineering & Bioproducts Research Center, Yonsei University, Seoul, Korea) Source :  PlantaMedica, v. 66 (3): p. 273-274, 2000 Title :  ALPHA-GLYCOSIDASE INHIBITORY ACTIVITY OFHEXAGAL-LOYIGLUCOSE FROM THE GALLS OF QUERCUS INFECTORIA Abstract :      Hexagalloyiglucose (3-0-digalloyl-1,2,4,6-tetra-O-galloyl-beta-D-glucose) isolated from the methanoi extractof the galls of Quercus infectoria (MAYAPHALA), significantly inhibitedalpha-glycosidases such as sucrose, maltase and isomaltase. Its inhibitory activity was comparable to acarbose being used as hypoglycemic agent, while the inhibitory activity onalpha-arnylase was approximately 10 times lower than that of acarbose. The results indicate that, when compared to a carbose, hexagalloyiglucose might reduce the side effects by reducing inhibition of alp...

Abstract no :  4-1..4-DG-053 Author(s) :  Bikshapathi, T.; Tripathi, S.N.; Pandey, B.L Address :  (Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, UP, .India) Source :  Journal of Research in Ayurveda and Siddha, v. 17(3-4): p. 126-148, 1996 Title :  CLINICAL EVALUATION OF PICRORHIZA KURROA ROYLE. EX~ BENTH. (KUTKI) IN THE MANAGEMENT OF CHRONIC OBSTRUCTIVE AIRWAY DISEASE Abstract :      The trial was carried out using crude rhizome powder of Picrorhiza kurroa (KATUKI) as immunotherapy in high doses on patients of obstructive airway diseases. A significant reduction in the global score of respiratory signs and symptoms was observed along with reduction in the eosinophil count of the blood. There was significant improvement in the respiratory functions and viscosity of the sputum markedly decreased with one week of treatment.

Abstract no :  4-1..4-DG-054 Author(s) :  Calabrese, C.; Berman, S.H.; Babish, J.G.; Ma, X.; Shinto, L.; Dorr. M.; Wells. K.; Wells, K.; Wenner,C. A.; Standish, LJ Address :  (Bastyr University Research Institute, Bastyr University, Washington, USA) Source :  Phytotherapy Research, v. 14(5): p. 333-338, 2000 Title :  A PHASE I TRIAL OF ANDROGRAPHOLIDE IN HIV POSITIVE PATIENTS AND NORMAL VOLUNTEERS Abstract :      A phase 1 dose-escalating clinical trial of andrographolide from Andrographis paniculata (BHUNIMBA) was conducted in 13HIV positive patients and five HIV uninfected, healthy volunteers. No subjects used antiretroviral medications during the trial. The planned regimen was 5 mg/kg bodyweight for 3 weeks, escalating to l0 mg/kg bodyweight for 3 weeks, and to 20 mg/kg bodyweight for a final 3 weeks. A significant rise in the mean CD4+ lymphocyte level of HIV subject occurred after administration of 10 mg/kg andrographolide. There were n...

Abstract no :  4-1..4-DG-055 Author(s) :  Carai, M.A.M.; Agabio, R.; Bombardelli, E.;Bourov, 1.; Gessa, G.L.; Lobina, C.; Morazzoni, P.; Pani, M.; Reali, R.; Vacca, G.; Colombo, G Address :  (C.N.R. Center for Neuropharmacology, Cagliari, Italy) Source :  Fitoterapia, v. 71(Suppl.): p. S38-S42, 2000 s Title :  POTENTIAL USE OF MEDICINAL PLANTS IN THE TREATMENT OF ALCOHOLISM Abstract :      The most relevant experimental data on the reducing effect of some medicinal herbs on voluntary alcohol intake in animal models of alcoholism have been reviewed. Pueraria lobata, Tabermanthe iboga, Panax ginseng, Salvia miltiorrhiza and Hypericum perforatum () proved to be effective in decreasing alcohol consumption. Reduction of alcohol absorption from the gastrointestinal system appeared to be a common feature among most of the above, plants. These data suggest that medicinal plants may constitute novel and effective pharmacotherapies for alcoholism.

Abstract no :  4-1..4-DG-056 Author(s) :  Devidas, K.V.; Radhakrishnan, P.; Warrier,P.K. Address :  (Clinical Research Unit (AY.), Kottakkal, Kerala,India) Source :  Journal of Research in Ayurveda and Siddha, v.20 (3-4): p. 187-190, 1999 Title :   EFFECT OF NIMBADIN IN THE TREATMENT OF PARINAMASULA. Abstract :      Nimbadin extracted from the oil of Nimba seeds (Azadirachta indica (NIMBA)) was administered (100 mg twice daily) in 13 cases of active duodenal ulcer for a period of 60 days. Among 13 patients treated 3 showed complete ulcer healing, 5 were in the healing process and remaining 5 did not show any improvement.

Abstract no :  4-1..4-DG-057 Author(s) :  Goyal, D.K.; Tiwari, S.K Address :  (MaharajaAgrasena Nagar, Near Kitha Klin, Bisalpur Road, HarunaNagala, Bareilly, UP, India) Source :  Journal of Research in Ayurveda and Siddha, v. 20(3-4): p. 93-100, 1999 Title :  STUDY ON SADABAHAR (VINCAROSEA LINN.) IN MADHUMEHA (DIABETES MELLITUS) Abstract :      The leaves of Sadabahar (Vinca rosea (TRINA RASNA)) were selected for their antidiabetic activity. The drug was administered in the form of paste (10 Gms, fresh leaves paste daily in two divided doses) to selected patients for 10 days. Significant fall in blood sugar level after one month treatment was observed.

Abstract no :  4-1..4-DG-058 Author(s) :  Gupta, P.P.; Dubey, S.D.; Mishra, J.K.; Ojha, J.K Address :  (Department of TB, Chest and Allergic Disease, IMS, Banaras Hindu University, Varanasi, UP, India) Source :  Journal of Research in Ayurveda and Siddha, v. 20(3-4): p. 191-194, 1999 Title :  A COMPARATIVE STUDY ON BRIHATI AND KANTAKARI IN SHVASA AND KASA Abstract :      Varies preparations of whole parts of Brihati and Kantakari have been used in Shvasa and Kasa in ancient Ayurvedic literature. Botanically, Brihati is identified as Solarium indicum while Kantakari as Solanum surattense (KANTAKARI). In this study water decoction of Brihati and Kantakari were prepared and studied to evaluate their efficacy in the patients of Shvasa (bronchial asthma) and Kasa (cough). Results of study suggest that the effect of Kantakari decoction was better than Brihati decoction on different clinical parameters like dyspnoea, cough, daily bouts of asthma pe...

Abstract no :  4-1..4-DG-059 Author(s) :  Hollister, L.E Address :  (Harris County Psychiatric Center, 2800 South Macgregor way, Houston, TX, Hous-ton, TX 77021, USA) Source :  Journal of Cannabis Therapeutics, v. 1(1): p. 5-27, 2001 Title :  MARIJUANA (CANNABIS) AS MEDICINE Abstract :      The modern published literature on the therapeutic potentials of cannabis has been reviewed. A pure preparation of the major active component, delta-9-tetrahydrocannabinol (THC), Marinol(R) ordronabinol, is available for treating nausea and vomiting associated with cancer chemotherapy and as an adjunct to weight loss in patients with wasting syndrome associated with AIDS. Although such approval currently applies only to orally administered THC, for practical purposes smoked marijuana should also be expected to be equally effective. Promising leads, although often fragile, suggest possible uses for treating chronic pain syndromes, neurological disease with...

Abstract no :  4-1..4-DG-060 Author(s) :  Iorno, I Address :   (Universidad de Granada, Facultadde lekas, Departamento de Estudios Semfticos, 18071Granada, Spain) Source :  Journal of Cannabis Therapeutics, v. 1(1): p. 63-70, 2001 Title :  THE THERAPEUTIC USE OF CANNABIS SATIVA (L.) IN ARABIC MEDICINE Abstract :      Arab scientists were several centuries ahead of our current knowledge of the curative power of hemp (Cannabis sativa Cannabinaceae). Modern, Western scientific literature ignores their contribution on the subject. The therapeutic uses of the plant in Arabic medicine from the 8th to the 18thcentury have been reviewed. Arab physicians knew and used its diuretic, anti-emetic, anti-epileptic, anti-inflammatory, painkilling and antipyretic properties, among others.

Abstract no :  4-1..4-DG-061 Author(s) :  Kamble, S.M.; Jyotishi, G.S.; Kamalakar,P.L.; Vaidya, S.M Address :  (Govt. Medical College, Nagpur, Maharashtra, India) Source :  Journal of Research in Ayurveda and Siddha, v. 17(1-2): p. 77-84, 1996 Title :  EFFICACY OF COCCINIA INDICA W. & A. IN DIABETES MELLITUS Abstract :      Trial of indigenous preparation from Coccinia indica (BIMBI) leaves was conducted in 30 non insulin dependent (NIDDM)diabetic patients. The drugs were found to exert protective influence against hyperlipidemia along with the control of hyperglycemia.

Abstract no :  4-1..4-DG-062 Author(s) :  Moreau de Tours, M Address :  -- Source :  Journal of Cannabis Therapeutics, v. 1(1): p. 89-94, 2001 Title :  LYPEMANIA WITH STUPOR; TENDENCY TO DEMENTIA- TREATMENT BY THE EXTRACT (RESINOUS PRINCIPLE) OF CANNABIS INDICA - CURE BICETRE HOSPICE (TRANSLATED FROM FRENCH BY ETHAN RUSSO) Abstract :      Case of a patient, an eighteen year old boy, who was cured by Cannabis indica (BHANGA) during 1857 is described. He was administered 5 centigram' pill of hashish which was in-creased to 30 centigrams gradually. A cup of black coffee was given half an hour after the drug. He responded to the drug after six months of treatment and was cured.

Abstract no :  4-1..4-DG-063 Author(s) :  Padhi, M.M.; Dash, N.C.; Badapanda, M.S.; Nanda, G.C Address :  (Central Research Institute (Ay.), Bhubaneswar751 009, Orissa, India) Source :  Journal of Research in Ayurveda and Siddha, v. 19 (1-2): p.9-21, 1998 Title :  STUDY OF THE EFFECT OF TWO FORMULATIONS MADE WITH THE PLANT LYGODIUM FLEXUOSUM SW. AS LOCAL APPLICATION IN THE CASES OF VICHARCHIKA (ECZEMA) Abstract :      The clinical efficacy of two formulations made with the plant Lygodium flexuosum as topical application was examined. In the cases of wet eczema, the paste of leaves has shown better results; while in dry eczema the oil boiled with its root has shown better effect and both are highly significant in comparison with placebo treatment.

Abstract no :  4-1..4-DG-063 Author(s) :  Padhi, M.M.; Dash, N.C.; Badapanda, M.S.; Nanda, G.C Address :  (Central Research Institute (Ay.), Bhubaneswar751 009, Orissa, India) Source :  Journal of Research in Ayurveda and Siddha, v. 19 (1-2): p.9-21, 1998 Title :  STUDY OF THE EFFECT OF TWO FORMULATIONS MADE WITH THE PLANT LYGODIUM FLEXUOSUM SW. AS LOCAL APPLICATION IN THE CASES OF VICHARCHIKA (ECZEMA) Abstract :      The clinical efficacy of two formulations made with the plant Lygodium flexuosum as topical application was examined. In the cases of wet eczema, the paste of leaves has shown better results; while in dry eczema the oil boiled with its root has shown better effect and both are highly significant in comparison with placebo treatment.

Abstract no :  4-1..4-DG-064 Author(s) :  Prakash, S.; Rai, N.P Address :  (Department of Kayachikitsa, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, UP, India Source :  Journal of Research in Ayurveda and Siddha, v. 17(1-2): p. 58-68, 1996 Title :  ROLE OF TINOSPORA CORDIFOLIA (WILLD.) MIERS., (GUDUCHI) IN THE TREATMENT OF INFECTIVE HEPATITIS Abstract :      Twenty patients of infective hepatitis (jaundice) were given four tablets (500 mg each) thrice a day, orally with fresh water for 4 weeks. Comparison between before and after treatment of these patients showed that (Tinospora cordifolia (GUDUCHI)) plays an important role in relieving the symptoms as well as normalization of altered liver functions. The majority of cases i.e.15 cases (75 percent) were cured and 5 cases (25 percent) improved after treatment with Tinospora cordifolia (GUDUCHI).

Abstract no :  4-1..4-DG-065 Author(s) :  Prasad, M.; Rai, N.P.; Tripathi, K Address :  (Department of Medicine, I.M.S., Banaras Hindu University, Varanasi 221 005, UP, India) Source :  Journal of Research in Ayurveda and Siddha, v. 17(1-2): p.69-76, 1996 Title :  EFFECT OF TINOSPORA CORDIFOLIA (WILID.) MIERS. (AMRITA) ON KAMALA ROGA (JAUNDICE) Abstract :      Tinospora cordifolia (GUDUCHI) was tried in 20 patients of Kamala ROGA (Jaundice of viral origin). The drug provided good clinical relief as well as biochemical improvement.

Abstract no :  4-1..4-DG-066 Author(s) :  Rajalakshmi, S.; Sivanandam, G.; Veluchamy, G Address :  (Central Research Institute(S), Chennai106, TN, India) Source :  Journal of Research in Ayurveda and Siddha,. 18(3-4): p. 141-146, 1997) Title :  CLINICAL EVOLUTION OF ATHIMATHURAM IN VIRAL HEPATITIS (A CONTROLLED STUDY) Abstract :      A clinical trial was carried out with placebo control on two identical groups of patients of viral hepatitis to evaluate the effect of ATHIMATHURAM (Glycyrrhiza glabra (YASTI)) against viral hepatitis. The clinical and biochemical clearance of the disease was accelerated in drug group as compared with its placebo control as evidenced by their laboratory parameters.

Abstract no :  4-1..4-DG-067 Author(s) :  Saroja, P.R.; Sivaprakasam/K.; Veluchamy, G Address :  (Central Research Institute (S), Arumbakarn, Chennai600 106, TN, India) Source :  Journal of Research in Ayurveda and Siddha, v. 19(3-4): p.128-131, 1998 Title :  ROLE OF CHUNDAIVATTRAL CHURNAM IN THE MANAGEMENT OF (NON-SPECIFIC DIARRHEA) ATHISARAM Abstract :      CHUNDAIVATTRAL CHURNAM contains Chundaivattral (Solanum torvum (BRIHATI BH.)) as a main ingredient and is recommended for the treatment of diarrhea in Siddha literature. About 25 cases were included in this study and majority of them responded well and 25 percent gave only mild response. The pathological investigation of stool was done before and after treatment to rule out worms infestation and other infections responsible for causing diarrhea.

Abstract no :  4-1..4-DG-068 Author(s) :  Shetty, B.R.; Seshadri, C.; Sundaresen, T.P.; Rajagopalan, V.; Srinivasan, K.; Sitaraman, R.; Revathy, R.; Janaki, K.; Rama Rao, B Address :  (Dr.A.Lakshmipathi Research Centre for Ayurveda, V.H.S.Campus, T.T.T.I. Post, Chennai 113, TN, India) Source :  Journal of Research in Ayurveda and Siddha, v.18(3-4): p. 108-117, 1997 Title :  STUDIES ON THE RASAYANA EFFECT OF A GERIATRIC FORMULATION IN APPARENTLY NORMAL AGED PERSONS Abstract :      The Rasayana (healthful longevity) effect of a geriatric formulation of 6 herbal drugs on 38 healthy male volunteers was assessed. Extensive clinical, psychological, bio-chemical and anthropometric tests were selected as parameters of assessment. The treatment period was six months. Results indicate that this compound drug is a comprehensive and balanced drug formulation, capable of restoring the age related impaired functions, viz.,joint pains, memory deficits, etc...

Abstract no :  4-1..4-DG-069 Author(s) :  Shukia, R.; Sharma, S.B.; Puri, D.; Murthy, P.S Address :  (Department of Biochemistry, University College of Medical Sciences and GTB Hospital, Shahdara 110095, Delhi, India) Source :  J K Science, v. 2(3): p. 128-131, 2000 Title :  INDIGENOUS DRUGS FOR DIABETES MELLITUS Abstract :      Extracts from several plants were prepared and evaluated against induced diabetes in animals an in some diabetic patients. From plants like Allium cepa (PALANDU), Allium sativum (LASUNA), Ficus bengalensis (VATA), Gymnema sylvestre (MESHASRINGI) etc., active hypoglycemic constituents were isolated and their mechanism of action studied. Most of them stimulated blood insulin level in NIDDM patients as in diabetic animals. Information on few commonly ant diabetic plants with proven activity have been reviewed ~

Abstract no :  4-1..4-DG-070 Author(s) :  Shukia, U.; Sharma, A.K Address :   (P.G.Department of Kaya Chikitsa, National Institute of Ayurveda, Jaipur302 002, Rajasthan, India) Source :  Journal of Research in Ayurveda and Siddha, v. 20(3-4): p. 178-186, 1999 Title :  ROLE OF TAGARA MULA CHURNA IN ESSENTIAL HYPERTENSION Abstract :      Twenty patients affected by essential hypertension were treated with Tagara Mula Churna (Valeriana wallichi (TAGARA)i) 5 gm BD, with lukewarm water for 30-40 days. The results were encouraging in the cases of mild essential hypertension and were found to be statistically significant.

Abstract no :  4-1..4-DG-071 Author(s) :  Swamy, G.K.; Bhattathiri, P.P.N.; Rao, P.V.; Acharya, M.V.; Bikshapathi, T Address :  (Regional Research Centre (Ay.), Rehari, Jammu, JK, India) Source :  Journal of Research in Ayurveda and Siddha, v. 18(1-2): p. 21-27, 1997 Title :  CLINICAL EVALUATION OF SIRISA TWAK KVATHA IN THE MANAGEMENT OF TAMAKA SHWASA (BRONCHIAL ASTHMA) Abstract :      The decoction of Sirisa (Albizzia lebbeck (SIRISHA)) stem bark was found to be effective against bronchospasm induced by histaminic acid phosphate and shown to exert disodiumcromoglycate like action on mast cells. Results of clinical trials conducted with Sirisa Twak Kvatha on 19 TAMAKA SHWASA patients are reported. A considerable fall of total W.B.C. count (P more than 0.01), eosinophil count (P more than 0.001), ESR (0.01) and increase in the levels of PEFR (P less than 0.001) were observed. The effect of treatment based on the subjective and objective param...

Abstract no :  4-1..4-DG-072 Author(s) :  Aguiyi, J.C.; Obi, C.I.; Gang, S.S.; Igweh, A.C Address :  (Department of Pharmacology and Clinical Pharmacy, University of Jos, Jos, Nigeria) Source :  Fitoterapia, v. 71(4): p.444-446, 2000 Title :  HYPOGLYCEMIC ACTIVITY OF OCIMUM GRATISSIMUM IN RATS Abstract :      The hypoglycemic effect of the methanol extract of Ocimum gratissimum (TULASI BH.) leaves was evaluated in normal and alloxan-induced diabetic rats. Intraperitoneal injection of the extract (400 mg/kg) significantly reduced plasma levels both in normal and diabetic rats by 56 and 68 percent, respectively.

Abstract no :  4-1..4-DG-073 Author(s) :  AI-Yahya, M.A.; AI-Farhan, A.H.; Adam, S.E.I Address :  ( Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, King Saud University, P.O.Box 1482, Buraidah, AI-Qassim, Saudi Arabia) Source :  Fitoterapia, v. 71(4): p. 385-391, 2000 Title :  PRELIMINARY TOXICITY STUDY ON THE INDIVIDUAL AND COMBINED EFFECTS OF CITRULLUS COLOCYNTHIS AND NERIUM OLEANDER IN RATS Abstract :      The toxicity of diet containing 10 percent of Citrullus colocynthis (INDRAVARUNI) fruits or 10 percent of Nerium oleander (KARAVIRA BH.) leaves or their 1: 1 mixture (5 percent plus 5 percent) for rats treated for 6 weeks was determined. Dullness, ruffled hair, de-creased body weight gains and feed efficiency, and enterohepatonephropathy characterized treatment with Citrullus colocynthis (INDRAVARUNI) and N .oleander given alone. Diarrhea was a prominent sign of C. colocynthis poisoning. Organ lesions ...

Abstract no :  4-1..4-DG-074 Author(s) :  Ali, S.; Ansari, K.A.; Jafry, M.A.; Kabeer, H.; Diwakar, G Address :   (Department of Ilmul-Advia, Faculty of Medicine, Hamdard University, New Delhi 110 062, India) Source :  Journal of Ethno pharmacology, v. 71(3): p. 359-363, 2000 Title :  NARDOSTACHYS JATAMANSI PROTECTS AGAINST LIVER DAMAGE INDUCED BY THIOACETAMIDE IN RATS Abstract :      Pretreatment of ethanol extract of Nardostachys jatamansi (JATAMAMSI) rhizomes (800 mg/kg body wt, orally) for three consecutive days significantly ameliorated the liver damage in rats exposed to the hepatotoxic compound thioacetamide. Elevated levels of serum transaminases (aminotransferases) and alkaline phosphatase, observed in thioacetamide alone treated group of animals, were significantly lowered in N. jatamansi pretreated rats. Pretreatment of the animals with the extract also resulted in an increase in survival of rats intoxicated with LD90 dose of the h...

Abstract no :  4-1..4-DG-075 Author(s) :  Anis, K.V.; Kuttan, G.; Kuttan, R Address :  (Amala Cancer Research Centre, Amala Nagar, Trissur 680 553, Kerala, India) Source :   Amala Research Bulletin, v. 19: p. 58-64, 1999 Title :  EFFECT OF ISOQUINOLINE ALKALOID, BERBERINE AS AN ADJUVANT DURING CHEMOTHERAPY AND RADIATION THERAPY Abstract :      Berberine was found to be toxic to L 924 cells in culture (IC50= 40 micro g/ml) and to mice when given in acute (LD50=50mg/kg b wt.i.p.) or chronic dosage (LD=15mg/kg b.wt.)/ day /10 day i.p). At non-toxic concentrations berberine was found to inhibit the tumor induced by Dalton’s lymphoma ascites tumor cells. The drug was found to be more active when given intraperitonially. Berberine also potentate therapeutic activity of radiation, cyclophosphomide as well as hyperthermia. In solid tumor volume was found reduced by the berberine. These results indicate the use of berberine as an adjuvant response mo...

Abstract no :  4-1..4-DG-076 Author(s) :  Antony, S.; Kuttan, R.; Kutta, N, Address :  (Amala Cancer Research Centre, Amala Nagar, Trissur 680 553, Kerala, India) Source :   Amala Research Bulletin, v. 19: p. 24-28, 1999 Title :  EFFECT OF ISCADOR ON CYTOKINE LEVELS OF METASTATIC TUMOR BEARING ANIMALS Abstract :      Iscador, an extract from Viscum album (SVARNA BANDAKA) plant increased the levels of various cytokines in normal animals. B16FIO, metastatic tumor bearing animals showed lowered levels of IFN- gamma, IL-2 and elevated levels of GM-CSF and TNF-alpha. Treatment with Iscador increased the levels of IFN-gamma and IL-2 in tumor bearing mice whereas GM-CSF and TNF-alpha levels were reduced significantly.

Abstract no :  4-1..4-DG-077 Author(s) :  Back, S.H.; Kirn, Y.O.; Kwag, J.S.; Choi, K.E.; Jung, W.Y.; Han, D.S Address :  (Department of Chemistry, Wonkwang University, Iksan 570-749, Korea) Source :  Archives of Pharmacal Research, v. 21(3): p. 353-356, 1998 Title :  BORON TRI-FLUORIDE ETHERATE ON SILICA-A MODIFIED LEWIS ACID REAGENT (VII). ANTITUMOUR ACTIVITY OF CANNABIGEROL AGAINST HUMAN ORAL EPITHELOID CARCINOMA CELLS Abstract :      Geraniol, olivetol, cannabinoids and 5-fluorouracil, active constituents of Cannabis saliva were tested for their growth inhibitory effects against human oral epitheloid carcinoma cell lines and fibroblasts using two different3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazoliumbromide assay and sulforhodamine B protein assay. Cannabigerol exhibited the highest growth-inhibitory activity against the cancer cell lines.

Abstract no :  4-1..4-DG-078 Author(s) :  Barua, C.C.; Gupta, P.P.; Patnaik, G.K.;Misra-Bhattacharya, S.; Goel, R.K.; Kulshrestha, D.K.; Dubey, M.P.; Dhawan, B.N Address :   (Division of Phamacology, Central Drug Research Institute, Lucknow, UP, India) Source :  Pharmaceutical Biology, v. 38(3): p. 161-166, 2000 Title :  IMMUNOMODULATORY EFFECT OF ALBIZZIA LEBBECK Abstract :      The hot aqueous extract of the bark of Albizzia lebbeck (SIRISHA) and its butanolic fraction were administered once daily for one week in mice, immunized previously with sheep red blood cells (SRBC). At the dose levels tested (6.25, 12.5 and 25 mg/kg.p.o.). A lebbeck treated mice developed higher serum antibody titers compared to the vehicle treated group and the effect was comparable to the standard drug muramyldipeptide (MDP). Delayed type hypersensitivity response was suppressed in SRBC immunized mice treated with A. lebbeck extract. The macrophage migration inde...

Abstract no :  4-1..4-DG-079 Author(s) :  Bharti; Singh, R.H.; Chansouria, J.P.N Address :  (Department of Kayachikitsa and C.E.M.S., Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, UP, India) Source :  Hindi;Recd.2000; Journal of Research in Ayurveda and Siddha, v. 17(3-4): p. 162-168, 1996 Title :  HYPOGLYCEMIC ACTIVITY OF MELIA AZADIRACHTA LINN. BARK Abstract :      The hypoglycemic activity of different extracts of Melia azadirachta (MAHANIMBA) bark in normal and alloxanised albino rats was investigated. Significant hypoglycemic activity was observed in aqueous extract of the bark. NIMBA bark is a constituent of TRIKANTAKADYA SNEHA mentioned for KAPHAJA and VATAJA PRAMEHA (Caraka Chikitsa, 6/39). Susruta prescribed NIMBA KASAYAM for SURAMEHINAM. Apart from nimidin (bitter principle from neem seed oil), it’s TIKTA, KASAYA RASA, LAGHU GUNA and KATU VIPAKA may explain its PRAMEHAHARA (antidiabetic activity).

Abstract no :  4-1..4-DG-080 Author(s) :  Burits, M.; Bucar, F Address :  (Institute of Pharmacognosy, Karl-Franzens-University of Graz, Graz, Austria) Source :  Phytotherapy Research, v. 14(5): p. 323-328, 2000 Title :  ANTIOXIDANT ACTIVITY OF NIGELLA SATIVA ESSENTIAL OIL Abstract :      The essential oil of black cumin seeds Nigella sativa (UPAKUNCHIKA  ) was tested for a possible antioxidant activity. Theymoquinone and the components carvacrol, t-anethole and 4-terpineol demonstrated respectable radical scavenging property. These four constituents and the essential oil exhibited variable antioxidant activity when tested in the assay for non-specific hydrogenation or electron donating activity. They were also effective OH radical scavenging agents in the assay for non-enzymatic lipid peroxidation in liposomes and the deoxyribose degradation assay. GC-MS analysis of the essential oil obtained from six different samples of Nigella sativ...

Abstract no :  4-1..4-DG-081 Author(s) :  Capasso, R.; Pinto, L.; Vuotto, M.L.; DiCarlo, G Address :  (Department of Experimental Pharmacology, University of Naples, 'Federico II', Via D.Montesanoo, 49, 80131 Naples, Italy) Source :  Fitoterapia, v. 71(Suppl.): p. S131-S137, 2000 Title :  PREVENTIVE EFFECT OF EUGENOL ON PAF AND ETHANOL-INDUCED GASTRIC MUCOSAL DAMAGE Abstract :      The antiulcerogenic activity of eugenol, a natural compound obtained from Myristica fragrans (JATIPHALA) has been discussed. Gastric ulcers, induced by administration of two ulcerogenic agents, i.e. platelet activating factor (PAF) and ethanol, were dose-dependently and significantly reduced by eugenol (10-100 mg/kg, p.o.)pretreatment. Eugenol was able to reduce not only the number of ulcers but also the gravity of lesions.

Abstract no :  4-1..4-DG-081 Author(s) :  Capasso, R.; Pinto, L.; Vuotto, M.L.; DiCarlo, G Address :  (Department of Experimental Pharmacology, University of Naples, 'Federico II', Via D.Montesanoo, 49, 80131 Naples, Italy) Source :  Fitoterapia, v. 71(Suppl.): p. S131-S137, 2000 Title :  PREVENTIVE EFFECT OF EUGENOL ON PAF AND ETHANOL-INDUCED GASTRIC MUCOSAL DAMAGE Abstract :      The antiulcerogenic activity of eugenol, a natural compound obtained from Myristica fragrans (JATIPHALA) has been discussed. Gastric ulcers, induced by administration of two ulcerogenic agents, i.e. platelet activating factor (PAF) and ethanol, were dose-dependently and significantly reduced by eugenol (10-100 mg/kg, p.o.)pretreatment. Eugenol was able to reduce not only the number of ulcers but also the gravity of lesions.

Abstract no :  4-1..4-DG-083 Author(s) :  Chattopadhyay, R.R Address :   (Biometry Research Unit, Indian Statistical Institute, 203 Barrackpore Trunk Road, Calcutta 700 035, WB, India) Source :   Journal of Ethnopharmacology, v. 67(3):p. 373-376, 1999 Title :  POSSIBLE MECHANISM OF ANT HYPERGLYCEMIC EFFECT OF AZADIRACHTA INDICA LEAF EXTRACT: PART V Abstract :      Effect of Azadirachta indica (NIMBA) leaf extract on serotonin inhibition in glucose mediated insulin release in rat pancreas was studied in vitro to elucidate the possible mechanism of anti hyperglycemic effect of A. indica leaf extract. A. indica leaf extract blocks significantly (P less than 0.05) the inhibitory effect of serotonin on insulin secretion mediated by. glucose.

Abstract no :  4-1..4-DG-084 Author(s) :  Chithra, V.; Leelamma, S Address :  (Department of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram 695 581, Kerala, India) Source :   Journal of Ethnopharmacology, v. 71(3): p. 457-463, 2000 Title :  CORIANDRUM SATIVUM- EFFECT ON LIPID METABOLISM IN 1, 2-DIMETHYLHYDRAZINE INDUCED COLON CANCER Abstract :      The biochemical effect of coriander seeds on lipid parameters in 1,2-dimethyl hydrazine(DMH) induced colon cancer in rats are reported. The concentrations of cholesterol and cholesterol to phospholipids ratio decreased while the level of phospholipid increased significantly in the DMH control group compared to the spice administered group. Fecal dry weight, fecal neutral sterols and bile acids showed a sharp increase in the coriander-fed group compared with the DMH administered group. Coriander was found to playa protective role against the deleterious effects in lipid metabol...

Abstract no :  4-1..4-DG-085 Author(s) :  Choi, J.J.; Yoon, K.N.; Lee, S.K.; Lee, Y.H.; Park, J.H.; Kirn, W.Y.; Kirn, J.K.; Kirn, W.K Address :  (Department of Pharmacology, College of Medicine, Division of Neuroscience. Medical Research Center, Ewha Woman University, Seoul 158-056, Korea) Source :   Archives of Pharmacal Research, v.21 (3): p. 266-272, 1998 Title :  ANTITUMOUR ACTIVITY OF THE AQUEOUS-ALCOHOLIC EXTRACTS FROM UNRIPE COTTON. AN EXPOSURE OF MURINE B16 MELANOMA AND L1210LYMPHOMA CELLS TO THE AQUEOUS-ALCOHOLIC EXTRACTS FROM UN-RIPE COTTON BALLS OF GOSSYPIUM INDICUM RESULTED IN THEIR SEVERE DEATHS IN TIME- AND CONCENTRATION-DEPENDENT MANNERS. OF THE EXTRACTS, HYDROPHILIC FRACTIONS WERE MOST EFFICACIOUS FOR THE ANTITUMOUR ACTIVITY AND FOUND TO CONTAIN CERTAIN BALL OF GOSSYPIUM INDICUM Abstract :      amounts of catechin and its derivatives. The hydrophillic extract fraction had approximately 10 times more cytotoxic effects on B12 a...

Abstract no :  4-1..4-DG-086 Author(s) :  Datta, S.; Sinha, S.; Bhattacharyya, P Address :  (Department of Chemistry, Bose Institute 93/1, A.P.C. Road, Calcutta 700 009, WB, India) Source :  Journal of Ethnopharmacology, v. 67(3): p. 259-267, 1999 Title :  EFFECT OF A HERBAL PROTEIN, CI-I, ISOLATED FROM CAJANUS INDICUS ON IMMUNE RESPONSE OF CONTROL AND STRESSED MICE Abstract :      The effect of an herbal protein, Cl-1, purified from the leaves of Cajanus indicus was evaluated as a probable immunomodulator on immune response in control and stressed mice. In mice, sensitized with sheep red blood cells(SRBC), Cl-1 enhanced lgG level by 28 percent over control(P less than 0.05). Primary and secondary antibody response to SRBC and bovine serum albumin (BSA) were significantly increased in CI-I treated group. Furthermore Cl-I facilitated the delayed type of hypersensitivity (DTH) response to SRBC in sensitized mice and also enhanced leucocytes an...

Abstract no :  4-1..4-DG-087 Author(s) :  De, S.; Chakraborty, J.; Charaborty, R.N.; Das, S Address :  (Department of Cancer Chemoprevention, Chittaranjan National Cancer Institute, Calcutta 700 026, WB, India) Source :  PhytotherapyResearch, v. 14(5): p. 347-351, 2000 Title :  CHEMO PREVENTIVE ACTIVITY OF QUERCETIN DURING CARCINOGENESIS IN CERVIX UTERI IN MICE Abstract :      The chemo preventive action of quercetin, a bioflavonoid, present in many plants, was examined during20-methyl cholanthrene induced cervical neoplasia in Swiss albino mice. The effects were evaluated on the basis of histopathological observation of the cervical epithelium, micronucleus frequency in vaginal exfoliated cells and some biochemical parameters in the host liver. Quercetin was found to arrest or reverse the progression of cervical neoplasia. The micronucleus frequency was reduced following its administration. The potential ant carcinogenic effect of quercetin...

Abstract no :  4-1..4-DG-088 Author(s) :  Dhuley, J.N Address :  (Department of Pharmacology and Toxicology, Research Division, Hindustan Antibiotics Ltd., Pimpri, Pune 411 018, Maharashtra, India) Source :  Journal of Ethnopharmacology, v. 67(3): p. 361-365, 1999 Title :  ANTITUSSIVE EFFECT OF ADHATODA VASICA EXTRACT ON MECHANICAL OR CHEMICAL STIMULATION-INDUCED COUGHING IN ANIMALS Abstract :      The antitussive activity of Adhatoda vasica (VASA) (AV) extract was evaluated in anaesthetized guinea pigs and -rabbits and in un-anaesthetized guinea pigs. AV was shown to have a good antitussive activity. Intravenously, it was 1/20-1/40 as active as codeine on mechanically and electrically induced coughing in rabbits and guinea-pigs. After oral administration to the guinea-pig the antitussive activity of AV was similar to codeine against coughing induced by irritant aerosols.

Abstract no :  4-1..4-DG-089 Author(s) :  Escribano, J.; Jose, M.; Diaz-Guerra, M.;Riese, H.H.; Alvarez, A.; Proenza, R.; Fernandez, J.A Address :  (Seccion de Bioteenologia, IDR, Universidad de Castilla-LaMancha, Albacete, Spain) Source :  Planta Medica., v.66(2): p. 157-162, 2000 Title :  THE CYTOLYTIC EFFECT OF A GLYCOCONJUGATE EXTRACTED FROM CORMS OF SAFFRON PLANT (CROCUS SATIVUS) ON HUMAN CELL LINES IN CULTURE Abstract :      Corms of Crocus sativus (KUMKUMAM) L.(Iridaceae) contain a glycoconjugate, proteoglycan which cause plasma membrane damage, allowing movements of both calcium and macro-molecules, and leading to cell lysis. Analysis of DNA fragmentation showed that cell death was not mediated by apoptosis. This molecule is active against human tumor cells derived from fibro sarcoma, cervical epithelioid carcinoma and breast carcinoma, with IC50 values of 7, 9 and 22microg/ml, respectively. The proteoglycan is about 8 times more cyt...

Abstract no :  4-1..4-DG-090 Author(s) :  Gebhardt, R Address :  (Institut fur Biochemie, Mediz-inische Fakultat, Universitat Leipzig, 04103 Leipzig, Germany) Source :  PlantaMedica, v. 66(2): p. 99-105, 2000 Title :  IN VITRO SCREENING OF PLANT EXTRACTS AND PHYTO-PHARMACEUTICALS: NOVEL APPROACHES FOR THE ELUCIDATION OF ACTIVE COMPOUNDS AND THEIR MECHANISMS Abstract :      The advantages of cell culture systems for the screening of active compounds in plant extracts and phytopharmaceuticals are discussed and exemplified for hepatocytes and nerve cells. Recent developments and new experimental techniques allow easy access even to complex specific functions of these cells and render it possible to draw conclusions about molecular mechanisms. These in vitro approaches, therefore, may contribute essentially to the reduction of animal use in such studies. Furthermore, they may give full insight into not only the therapeutic potential but also the...

Abstract no :  4-1..4-DG-091 Author(s) :  Guru, M.; Ravishanker, B Address :  (Department of Dravyaguna, Govt. Ayurveda College, Ballenger 760 001, Orissa, India) Source :   Journal of Research in Ayurveda and Siddha, v. 19(3-4): p. 139-144, 1998 Title :  HEPATOPROTECTIVE EFFECT OF PERGULARIA DAEMIA FORSK. IN RATS Abstract :      Pergularia daemia (UTTAMARANI) found throughout the hotter part of India and is in use as a folk remedy for jaundice in Orissa. To examine the claim, leaf juice of P. daemia with yoghurt was administered adlibitum in graded doses to rats before, during and after CC14 administration (2 ml/kg, 25 percent V/V in liquid paraffin-IP-two injections). Leaf juice failed to produce significant effect on the changes in liver weight and liver volume and biochemical parameters studied. His-to pathological examination of the liver showed that in rat~ receiving higher dose, liver damage was comparatively less.

Abstract no :  4-1..4-DG-092 Author(s) :  Hiremath, S.P.; Rudresh, K.; Badami, S.; Patil, S.B.; Patil, S.R Address :  (Department of Chemistry, Gulbarga University, Gulbarga 585 106, Karnataka, India) Source :  Journal of Ethnopharmacology, v. 67(3): p. 253-258, 1999 Title :  POST-COITAL ANTI-FERTILITY ACTIVITY OF ACALYPHA INDICA L. Abstract :      Four successive solvent extracts of the whole plant Acalypha indica (KUPPI (LAGHU)) were tested for post-coital antifertility activity in female albino rats. Of these, the petroleum ether and ethanol extracts were found to be most effective in causing significant anti-implantation activity. The antifertility activity was reversible on withdrawal of the treatment of the extracts. Both the extracts at 600 mg/kg body weight showed estrogenic activity. Histological studies of the uterus were carried out to confirm this estrogenic activity.

Abstract no :  4-1..4-DG-093 Author(s) :  Hsieh, M.T.; Peng, W.H.; Wu, C.IW.H Address :  (Institute of Chinese Pharmaceutical Sciences, China) Source :  Phytotherapy Research, v. 14(5): p. 375-377, 2000 Title :  THE AMELIORATING EFFECTS OF THE COGNITIVE-ENHANCING CHINESE HERBS ON SCOPOLAMINE-INDUCED AMNESIA IN RATS Abstract :      Of the ten Chinese herbs administered orally for weeks- Panax ginseng, (PG), Panox notoginseng (PNG),Dioscorea opposita (VARAHI BH.) (DO), Gastrodia elata (GE), Salvia miltiorrhita (SM), Acorus gramineus (AG), Coptis chinensis (CC), Polygonum multiflorum (PM), Cyperus rotundus (MUSTAKAM ) (CR) and Psoralea corylifolia (BAKUCHI) (PC) only PG, PNG, GE and CC prolonged the scopolamine (SCOP) shortened STL. PG, PNG, GE and CC administered orally for I week improved the SCOP-induced learning and memory deficit in rats.

Abstract no :  4-1..4-DG-094 Author(s) :  Jagadeeswaran, R.; Thirunavukkarasu, C.; Gunasekaran, P.; Ramamurthy, N.; Sakthisekaran, D Address :  (Department of Medical Biochemistry, Dr.A.L.M.PG Institute of Basic Medical Sciences, Taramani Campus, University of Madras, Chennai 600 113, TN, India) Source :  Fitoterapia, v. 71(4): p. 395-399, 2000 Title :  IN VITRO STUDIES ON THE SELECTIVE CYTOTOXIC EFFECT OF CROCETIN AND QUERCETIN Abstract :      Crocetin, a carotenoid present in red stigmatic lobes of Crocus sativus (KUMKUMAM) (5-20 microg/ml), quercetin (10-40 microg/ml), and cisplatin (60-180 microg/ml) used as a positive control drug, were tested against human rhabdomyosarcoma (RD) cells and African green monkey kidney (Vero) cells. The cell viability, morphological changes, and lactate dehydrogenize activity were assessed. RD cell growth was found to be inhibited dose dependently by the three tested compounds. Morphological observation by...

Abstract no :  4-1..4-DG-095 Author(s) :  Jairaj, P.; Ongkrajang.Y.; Thongpraditchote, S.; Peungvicha, P.; Bunyapraphatsara, N.; Opartkiattikul, N Address :  (Department of Physiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand) Source :   Phytotherapy Research, v. 14(5): p.388-391, 2000 Title :  GUAVA LEAF EXTRACT AND TOPICAL HAEMOSTASIS Abstract :      The effects of guava Psidium guajava (PERUKA) leaf extract on the bleeding time and three main mechanisms of haemostasis: vasoconstriction, platelet aggregation and blood coagulation, were investigated. The water extract of guava leaves did not shorten bleeding times in rats. Guava leaf extract potentiated the vascular muscle contraction induced in rabbits by phenylephrine, and when given alone it stimulated human platelet aggregation in vitro in a dose-dependent manner. On the other hand, it significantly prolonged blood coagulation; activated partial thromboplastin time (AP...