Skip to main content

ANTITUMOUR ACTIVITY OF THE AQUEOUS-ALCOHOLIC EXTRACTS FROM UNRIPE COTTON. AN EXPOSURE OF MURINE B16 MELANOMA AND L1210LYMPHOMA CELLS TO THE AQUEOUS-ALCOHOLIC EXTRACTS FROM UN-RIPE COTTON BALLS OF GOSSYPIUM INDICUM RESULTED IN THEIR SEVERE DEATHS IN TIME- AND CONCENTRATION-DEPENDENT MANNERS. OF THE EXTRACTS, HYDROPHILIC FRACTIONS WERE MOST EFFICACIOUS FOR THE ANTITUMOUR ACTIVITY AND FOUND TO CONTAIN CERTAIN BALL OF GOSSYPIUM INDICUM

Abstract no :  4-1..4-DG-085
Author(s) :  Choi, J.J.; Yoon, K.N.; Lee, S.K.; Lee, Y.H.; Park, J.H.; Kirn, W.Y.; Kirn, J.K.; Kirn, W.K
Address :  (Department of Pharmacology, College of Medicine, Division of Neuroscience. Medical Research Center, Ewha Woman University, Seoul 158-056, Korea)
Source :   Archives of Pharmacal Research, v.21 (3): p. 266-272, 1998
Title :  ANTITUMOUR ACTIVITY OF THE AQUEOUS-ALCOHOLIC EXTRACTS FROM UNRIPE COTTON. AN EXPOSURE OF MURINE B16 MELANOMA AND L1210LYMPHOMA CELLS TO THE AQUEOUS-ALCOHOLIC EXTRACTS FROM UN-RIPE COTTON BALLS OF GOSSYPIUM INDICUM RESULTED IN THEIR SEVERE DEATHS IN TIME- AND CONCENTRATION-DEPENDENT MANNERS. OF THE EXTRACTS, HYDROPHILIC FRACTIONS WERE MOST EFFICACIOUS FOR THE ANTITUMOUR ACTIVITY AND FOUND TO CONTAIN CERTAIN BALL OF GOSSYPIUM INDICUM
Abstract :      amounts of catechin and its derivatives. The hydrophillic extract fraction had approximately 10 times more cytotoxic effects on B12 and L1210 cells than on isolated urine thymocytes. High concentrations (greater than 150microg/ml) mainly induced necrotic cell death. At low concentrations (less than 100 microg/ml), not only necrosis but also apoptosis of the two tumor cell lines was induced. Certain ingredients of the cotton ball extract of G. indicum have been reported to show antitumour activity.

Comments

Post a Comment

Popular posts from this blog

A COMPARATIVE STUDY ON HYPOCHOLESTEROLAEMIC EFFECT OF ALLICIN, WHOLE GERMINATED SEEDS OF BENGAL GRAM AND GUGGULIPID OF GUM GUGGLU

Abstract no :  4-1..4-DG-205 Author(s) :  Ghorai, M.; Mandal, S.C.; Pal, M.; Pal, S.P.; Saha, B.P Address :  (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta 700 032, WB, India) Source :  Phytotherapy Research, v. 14(3): p. 200-202, 2000 Title :  A COMPARATIVE STUDY ON HYPOCHOLESTEROLAEMIC EFFECT OF ALLICIN, WHOLE GERMINATED SEEDS OF BENGAL GRAM AND GUGGULIPID OF GUM GUGGLU Abstract :      The daily use of allicin (active principle from Allium sativum (LASUNA)) and whole germinated Bengal gram (Cicer arietinum (CHANAKA)) seeds for 8 weeks led to a significant decrease in serum cholesterol levels in normal volunteers with no side effects. Guggulipid (gum of Commiphora mukul (GUGGULU)) therapy, significantly (p less than 0.001) reduced the mean serum cholesterol level. Allicin treatment significantly reduced the mean serum cholesterol level. The serum cholesterol value was reduced d...
Post a Comment
Read more

GERMINATED BARLEY FOODSTUFF IMPROVES CONSTIPATION INDUCED BY LOPERAMIDE IN RATS.

Author(s) :  . (Applied Bioresearch Center, Corporate Research and Development Division Kirin Brewery Company Limited, Miyaharacho 3, Takasaki, Gunma  370-1295, Japan), Address :  Kannuchi,0.; Hitomi, Y.; Agata, K.; Nakamura, T.; Fushiki, T Source :   Bioscience, Biotechnology and Biochemistry, v. 62(9): p. 1788-1790, 1998 Title :  GERMINATED BARLEY FOODSTUFF IMPROVES CONSTIPATION INDUCED BY LOPERAMIDE IN RATS. Abstract :      The effects of germinated barley (YAVA) foodstuff (GBF) derived from the aleurone and scutellum fractions of germinated barley low-lignified hemicellulose were examined in Sprague-Dawley rats with constipation induced by Loperamide by addition to the diet (2 mg/kg body weight). Bowel movements were higher in the GBF-fed rats than in the cellulose-fed rats used as control. Fecal water content was also higher in the GBF-fed rats. The concentration of short chain fatty acids in cecal content, especially butyrate, was signi...
Post a Comment
Read more

STUDIES ON ESSENTIAL OILS, PART-14; NATURAL PRESERVATIVES FOR BUTTER

Ayurveda is the science and know how of human living in a better way. It is perfected over thousands of years in India. This blog trying to explore all the secrets Ayurveda in a simple and palatable form and named it as "Ayurvedya". It is wish and grace of Pujya Sadguru Deva. JGD Abstract no :  3-1...4-SV-362 Author(s) :   (Chemistry Dept., Gorakhpur University, Gorakhpur 273 009, UP, India) Address :  Singh, G.:Kapoor, I.P.S; Pandey, S.K. Source :  Journal of Medicinal and Aromatic plant sciences,  v. 20(3): p. 739-739, 1998 Title :  STUDIES ON ESSENTIAL OILS, PART-14; NATURAL PRESERVATIVES FOR BUTTER Abstract :      Essential oils extracted from ten spice materials have been tested to prevent butter deterioration stored at room temperature. Butter oxidation and lypolysis were determined by measuring peroxide and acid values respectively. Most of the oils have been found to possess greater anti-hydrolytic effects than commercial prese...
Post a Comment
Read more