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GERMINATED BARLEY FOODSTUFF IMPROVES CONSTIPATION INDUCED BY LOPERAMIDE IN RATS.

Author(s) :  . (Applied Bioresearch Center, Corporate Research and Development Division Kirin Brewery Company Limited, Miyaharacho 3, Takasaki, Gunma  370-1295, Japan),
Address :  Kannuchi,0.; Hitomi, Y.; Agata, K.; Nakamura, T.; Fushiki, T
Source :   Bioscience, Biotechnology and Biochemistry, v. 62(9): p. 1788-1790, 1998
Title :  GERMINATED BARLEY FOODSTUFF IMPROVES CONSTIPATION INDUCED BY LOPERAMIDE IN RATS.
Abstract :      The effects of germinated barley (YAVA) foodstuff (GBF) derived from the aleurone and scutellum fractions of germinated barley low-lignified hemicellulose were examined in Sprague-Dawley rats with constipation induced by Loperamide by addition to the diet (2 mg/kg body weight). Bowel movements were higher in the GBF-fed rats than in the cellulose-fed rats used as control. Fecal water content was also higher in the GBF-fed rats. The concentration of short chain fatty acids in cecal content, especially butyrate, was significantly higher in the GBF-fed rats than in the cellulose-fed rats. These findings suggested that GBF help normalize defecation not only in diarrhea but also constipation

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