Skip to main content

GUAVA LEAF EXTRACT AND TOPICAL HAEMOSTASIS

Abstract no :  4-1..4-DG-095
Author(s) :  Jairaj, P.; Ongkrajang.Y.; Thongpraditchote, S.; Peungvicha, P.; Bunyapraphatsara, N.; Opartkiattikul, N
Address :  (Department of Physiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand)
Source :   Phytotherapy Research, v. 14(5): p.388-391, 2000
Title :  GUAVA LEAF EXTRACT AND TOPICAL HAEMOSTASIS
Abstract :      The effects of guava Psidium guajava (PERUKA) leaf extract on the bleeding time and three main mechanisms of haemostasis: vasoconstriction, platelet aggregation and blood coagulation, were investigated. The water extract of guava leaves did not shorten bleeding times in rats. Guava leaf extract potentiated the vascular muscle contraction induced in rabbits by phenylephrine, and when given alone it stimulated human platelet aggregation in vitro in a dose-dependent manner. On the other hand, it significantly prolonged blood coagulation; activated partial thromboplastin time (APTT) test (p less than 0.05). The higher the concentration of the extract, the longer APTT was ob-served. Water extract of guava leaves showed ambiguous effects on the haemostatic system. Guava leaf extract did not affect bleeding times, it stimulated vasoconstriction and platelet aggregation but it inhibited blood coagulation. Guava leaf extract has not been recommended as a haemostatic agent.

Comments

Post a Comment

Popular posts from this blog

EFFECT OF OCIMUM SANCTUM ROOTS EXTRACT ON SWIMMING PERFORMANCE IN MICE

Abstract no :  4-1..4-DG-240 Author(s) :  Maity, T.K.; Mandal, S.C.; Saha, B.P.; Pal, M Address :  ( Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta 700 032, WB, India) Source :  Phytotherapy Research, v. 14(2): p. 120-121, 2000 Title :  EFFECT OF OCIMUM SANCTUM ROOTS EXTRACT ON SWIMMING PERFORMANCE IN MICE Abstract :      Methanol extract, obtained from the roots of Ocimum sanctum (TULASI ) at a dose of 400 mg/kg, i.p. increased the swimming time suggesting a central nervous system stimulant and/or antistress activity. The effect produced by the extract was comparable to that of desipramine, an antidepressant drug.
Post a Comment
Read more

GERMINATED BARLEY FOODSTUFF IMPROVES CONSTIPATION INDUCED BY LOPERAMIDE IN RATS.

Author(s) :  . (Applied Bioresearch Center, Corporate Research and Development Division Kirin Brewery Company Limited, Miyaharacho 3, Takasaki, Gunma  370-1295, Japan), Address :  Kannuchi,0.; Hitomi, Y.; Agata, K.; Nakamura, T.; Fushiki, T Source :   Bioscience, Biotechnology and Biochemistry, v. 62(9): p. 1788-1790, 1998 Title :  GERMINATED BARLEY FOODSTUFF IMPROVES CONSTIPATION INDUCED BY LOPERAMIDE IN RATS. Abstract :      The effects of germinated barley (YAVA) foodstuff (GBF) derived from the aleurone and scutellum fractions of germinated barley low-lignified hemicellulose were examined in Sprague-Dawley rats with constipation induced by Loperamide by addition to the diet (2 mg/kg body weight). Bowel movements were higher in the GBF-fed rats than in the cellulose-fed rats used as control. Fecal water content was also higher in the GBF-fed rats. The concentration of short chain fatty acids in cecal content, especially butyrate, was signi...
Post a Comment
Read more

ANTIOXIDANT ACTIVITY AND TOTAL PHENOLICS IN SELECTED FRUITS, VEGETABLES, AND GRAIN PRODUCTS

Abstract no :  3-1...4-SV-360 Author(s) :   (Food Research program, Agriculture and Agri-Food Canada, Pacific Agri-Food Research Center, Summerland, British Columbia VOH IZO, Canada) Address :  Velioglu, Y.S.; Mazza, G.; Gao, L.; Oomah, B.D Source :  , J. of Agricultural & Food Chemistry, v.46(10): p.4113-7, 1998 Title :  ANTIOXIDANT ACTIVITY AND TOTAL PHENOLICS IN SELECTED FRUITS, VEGETABLES, AND GRAIN PRODUCTS Abstract :      The antioxidant activities and total phenolics of 28 plant products, including sunflower seeds, flaxseeds, wheat germ, buckwheat, and several fruits, vegetables and medicinal plants were determined. The total phenolic content, determined according to the Folin-Ciocalteu method, varied from 169 to 10548 mg/100 g of dry product. Antioxidant activity of methanolic extract evaluated according to the beta-carotene bleaching method expressed as AOX (deltalog A170/min), AA (percent inhibition relative to control), OR...
Post a Comment
Read more