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ANTIOXIDANT ACTIVITY OF NIGELLA SATIVA ESSENTIAL OIL

Abstract no :  4-1..4-DG-080
Author(s) :  Burits, M.; Bucar, F
Address :  (Institute of Pharmacognosy, Karl-Franzens-University of Graz, Graz, Austria)
Source :  Phytotherapy Research, v. 14(5): p. 323-328, 2000
Title :  ANTIOXIDANT ACTIVITY OF NIGELLA SATIVA ESSENTIAL OIL
Abstract :      The essential oil of black cumin seeds Nigella sativa (UPAKUNCHIKA  ) was tested for a possible antioxidant activity. Theymoquinone and the components carvacrol, t-anethole and 4-terpineol demonstrated respectable radical scavenging property. These four constituents and the essential oil exhibited variable antioxidant activity when tested in the assay for non-specific hydrogenation or electron donating activity. They were also effective OH radical scavenging agents in the assay for non-enzymatic lipid peroxidation in liposomes and the deoxyribose degradation assay. GC-MS analysis of the essential oil obtained from six different samples of Nigella sativa (UPAKUNCHIKA  ) seeds and from a commercial fixed oil showed that the qualitative composition of the volatile compounds was almost identical. Differences were mainly restricted to the quantitative composition.

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