Skip to main content

A COMPARATIVE STUDY ON HYPOCHOLESTEROLAEMIC EFFECT OF ALLICIN, WHOLE GERMINATED SEEDS OF BENGAL GRAM AND GUGGULIPID OF GUM GUGGLU

Abstract no :  4-1..4-DG-205
Author(s) :  Ghorai, M.; Mandal, S.C.; Pal, M.; Pal, S.P.; Saha, B.P
Address :  (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta 700 032, WB, India)
Source :  Phytotherapy Research, v. 14(3): p. 200-202, 2000
Title :  A COMPARATIVE STUDY ON HYPOCHOLESTEROLAEMIC EFFECT OF ALLICIN, WHOLE GERMINATED SEEDS OF BENGAL GRAM AND GUGGULIPID OF GUM GUGGLU
Abstract :      The daily use of allicin (active principle from Allium sativum (LASUNA)) and whole germinated Bengal gram (Cicer arietinum (CHANAKA)) seeds for 8 weeks led to a significant decrease in serum cholesterol levels in normal volunteers with no side effects. Guggulipid (gum of Commiphora mukul (GUGGULU)) therapy, significantly (p less than 0.001) reduced the mean serum cholesterol level. Allicin treatment significantly reduced the mean serum cholesterol level. The serum cholesterol value was reduced due to daily use of whole germinated Bengal gram seeds. The hypocholesterolaemic effects of allicin and whole germinated Bengal gram seeds were found to be comparable to the established standard reference, guggulipid. These two materials are herbal in origin and it is supposed to have a lesser risk-benefit ratio compared with other available synthetic drugs. The inclusion of these herbal products in the normal diet has been suggested to have an alternative effective measure for hypercholesterolemia.

Comments

Post a Comment

Popular posts from this blog

EFFECT OF OCIMUM SANCTUM ROOTS EXTRACT ON SWIMMING PERFORMANCE IN MICE

Abstract no :  4-1..4-DG-240 Author(s) :  Maity, T.K.; Mandal, S.C.; Saha, B.P.; Pal, M Address :  ( Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta 700 032, WB, India) Source :  Phytotherapy Research, v. 14(2): p. 120-121, 2000 Title :  EFFECT OF OCIMUM SANCTUM ROOTS EXTRACT ON SWIMMING PERFORMANCE IN MICE Abstract :      Methanol extract, obtained from the roots of Ocimum sanctum (TULASI ) at a dose of 400 mg/kg, i.p. increased the swimming time suggesting a central nervous system stimulant and/or antistress activity. The effect produced by the extract was comparable to that of desipramine, an antidepressant drug.
Post a Comment
Read more

GERMINATED BARLEY FOODSTUFF IMPROVES CONSTIPATION INDUCED BY LOPERAMIDE IN RATS.

Author(s) :  . (Applied Bioresearch Center, Corporate Research and Development Division Kirin Brewery Company Limited, Miyaharacho 3, Takasaki, Gunma  370-1295, Japan), Address :  Kannuchi,0.; Hitomi, Y.; Agata, K.; Nakamura, T.; Fushiki, T Source :   Bioscience, Biotechnology and Biochemistry, v. 62(9): p. 1788-1790, 1998 Title :  GERMINATED BARLEY FOODSTUFF IMPROVES CONSTIPATION INDUCED BY LOPERAMIDE IN RATS. Abstract :      The effects of germinated barley (YAVA) foodstuff (GBF) derived from the aleurone and scutellum fractions of germinated barley low-lignified hemicellulose were examined in Sprague-Dawley rats with constipation induced by Loperamide by addition to the diet (2 mg/kg body weight). Bowel movements were higher in the GBF-fed rats than in the cellulose-fed rats used as control. Fecal water content was also higher in the GBF-fed rats. The concentration of short chain fatty acids in cecal content, especially butyrate, was signi...
Post a Comment
Read more