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A COMPARATIVE STUDY ON HYPOCHOLESTEROLAEMIC EFFECT OF ALLICIN, WHOLE GERMINATED SEEDS OF BENGAL GRAM AND GUGGULIPID OF GUM GUGGLU

Abstract no :  4-1..4-DG-205
Author(s) :  Ghorai, M.; Mandal, S.C.; Pal, M.; Pal, S.P.; Saha, B.P
Address :  (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta 700 032, WB, India)
Source :  Phytotherapy Research, v. 14(3): p. 200-202, 2000
Title :  A COMPARATIVE STUDY ON HYPOCHOLESTEROLAEMIC EFFECT OF ALLICIN, WHOLE GERMINATED SEEDS OF BENGAL GRAM AND GUGGULIPID OF GUM GUGGLU
Abstract :      The daily use of allicin (active principle from Allium sativum (LASUNA)) and whole germinated Bengal gram (Cicer arietinum (CHANAKA)) seeds for 8 weeks led to a significant decrease in serum cholesterol levels in normal volunteers with no side effects. Guggulipid (gum of Commiphora mukul (GUGGULU)) therapy, significantly (p less than 0.001) reduced the mean serum cholesterol level. Allicin treatment significantly reduced the mean serum cholesterol level. The serum cholesterol value was reduced due to daily use of whole germinated Bengal gram seeds. The hypocholesterolaemic effects of allicin and whole germinated Bengal gram seeds were found to be comparable to the established standard reference, guggulipid. These two materials are herbal in origin and it is supposed to have a lesser risk-benefit ratio compared with other available synthetic drugs. The inclusion of these herbal products in the normal diet has been suggested to have an alternative effective measure for hypercholesterolemia.

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