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A COMPARATIVE EVALUATION OF SOME BLOOD SUGAR LOWERING AGENTS OF PLANT ORIGIN.

Abstract no :  4-1..4-DG-082
Author(s) :  Chattopadhyay, R.R
Address :  (Biometry Research Unit, Indian Statistical Institute, 203 Barrackpore Trunk Road, Calcutta 700 035, WB, India)
Source :  Journal of Ethnopharmacology, v. 67(3): p. 367-372, 1999
Title :  A COMPARATIVE EVALUATION OF SOME BLOOD SUGAR LOWERING AGENTS OF PLANT ORIGIN.
Abstract :      A comparison of blood sugar lowering activity of four medicinal plants (Azadirachta indica (NIMBA), Gymnema sylvestre (MESHASRINGI), Catharanthus roseus (TRINA RASNA) and Ocimum sanctum (TULASI )) were carried out against normal and streptozotocin-induced diabetic rat models. The plant extracts decreased the blood sugar level in varying degrees. Blood sugar lowering unit (BLU) of activity of each leaf extract and tolbutamide was calculated by ED50 values. Statistical analysis revealed significant (P less than 0.05) variation among the treatments as well as doses with regard to their blood sugar lowering capacity. A. indica leaf extract was found to have the most potent sugar-lowering activity followed by C. roseus, G. sylvestre and O. sanctum.

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