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ALPHA-GLYCOSIDASE INHIBITORY ACTIVITY OFHEXAGAL-LOYIGLUCOSE FROM THE GALLS OF QUERCUS INFECTORIA

Abstract no :  4-1..4-DG-052
Author(s) :  Iwang, J.K.; Kong, T.W.; Back, N.I.; Pyun, Y. R
Address :  (Department of Biomaterials Science and Engineering & Bioproducts Research Center, Yonsei University, Seoul, Korea)
Source :  PlantaMedica, v. 66 (3): p. 273-274, 2000
Title :  ALPHA-GLYCOSIDASE INHIBITORY ACTIVITY OFHEXAGAL-LOYIGLUCOSE FROM THE GALLS OF QUERCUS INFECTORIA
Abstract :      Hexagalloyiglucose (3-0-digalloyl-1,2,4,6-tetra-O-galloyl-beta-D-glucose) isolated from the methanoi extractof the galls of Quercus infectoria (MAYAPHALA), significantly inhibitedalpha-glycosidases such as sucrose, maltase and isomaltase. Its inhibitory activity was comparable to acarbose being used as hypoglycemic agent, while the inhibitory activity onalpha-arnylase was approximately 10 times lower than that of acarbose. The results indicate that, when compared to a carbose, hexagalloyiglucose might reduce the side effects by reducing inhibition of alpha-amylase.

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