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CORIANDRUM SATIVUM- EFFECT ON LIPID METABOLISM IN 1, 2-DIMETHYLHYDRAZINE INDUCED COLON CANCER

Abstract no :  4-1..4-DG-084
Author(s) :  Chithra, V.; Leelamma, S
Address :  (Department of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram 695 581, Kerala, India)
Source :   Journal of Ethnopharmacology, v. 71(3): p. 457-463, 2000
Title :  CORIANDRUM SATIVUM- EFFECT ON LIPID METABOLISM IN 1, 2-DIMETHYLHYDRAZINE INDUCED COLON CANCER
Abstract :      The biochemical effect of coriander seeds on lipid parameters in 1,2-dimethyl hydrazine(DMH) induced colon cancer in rats are reported. The concentrations of cholesterol and cholesterol to phospholipids ratio decreased while the level of phospholipid increased significantly in the DMH control group compared to the spice administered group. Fecal dry weight, fecal neutral sterols and bile acids showed a sharp increase in the coriander-fed group compared with the DMH administered group. Coriander was found to playa protective role against the deleterious effects in lipid metabolism in experimental colon cancer.

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