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A COMPARATIVE STUDY ON THE HYPOLIPIDEMIC ACTIVITY OF ELLEVEN DIFFERENT PECTINS

Abstract no :  2-1&2-DG-059
Author(s) :  Prassannakumar. G; Sudheesh. S; Ushakumari. B; Valsa.A. K;
Address :   Vijaykumar.C; Sandya & Vijayalaxmi.N.R. Department  of  Biochemistry, University of  Kerala,  Karivettam, Thiruvanathapuram - 695581, India.
Source :  Journal of Food Scienca and Technology, 1997, Vol.34, No.2,  103-107
Title :  A COMPARATIVE STUDY ON THE HYPOLIPIDEMIC ACTIVITY OF ELLEVEN DIFFERENT PECTINS
Abstract :      Inclusion  of  pectin-rich  fruits  and  vegetables  can  be regarded   as  one  of  the  primary  prevention  strategies   of hyperlipidemia.  But, it has been found that all pectins  do  not show  effective  hypolipidemic  activity.  Eleven  pectins   were screened  among which pectins from Carica papaya, (ERANDA KARKATI) Coccinia indica (Bimbi), Lycopersicum esculentum (Tamatur)  and cumns sativus (Trapusa) showed highly significant  hypolipidemic activity in albino rats, while  others were less significant or insignificant in their action.  Detailed studies on elucidating the mechanism of action of these  pectins revealed that hypolipidemic activity was mainly due to the  lower rate  of absorption and higher rate of degration and  elimination of  lipids.  The increased activity plasma  Lecithin  Cholesterol Acyl  Transferase activity [LCAT] in rats fed pectin can  account for the significant decrease in the concentration of cholesterol. The  higher activity of lipoprotein lipase in the adipose  tissue and  heart may be responsible for the decreased  concentration  of triglycerides in serum of rats fed pectin.

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