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PROTECTION OF THE FLOWERS OF PRUNUS PERSICA EXTRACT FROM ULTRAVIOLET B-INDUCED DAMAGE OF NORMAL HUMAN KERATINOCYTES

Abstract no :  4-1..4-DG-097
Author(s) :  Kirn, Y.H.; Yang, H.E.; Kirn, J.H.; Heo, M.Y.; Kim, H.P
Address :  (College of Pharmacy, Kangwon National University, Chunchon 200-701, Korea)
Source :  Archives of Pharmacal. Research, v. 23(4): p. 396-400, 2000
Title :  PROTECTION OF THE FLOWERS OF PRUNUS PERSICA EXTRACT FROM ULTRAVIOLET B-INDUCED DAMAGE OF NORMAL HUMAN KERATINOCYTES
Abstract :      Ethanol extract of the flowers of Prunus persica (AARUKA) (Ku-35; 100-1,000 microg/ml) inhibited the amount of14C-arachidonic acid/metabolites release from UVB-irradiated keratinocytes. Ku-35 also exhibited the protective activity against UV-induced cytotoxicity of keratinocytes and fibroblasts. In addition, Ku-35 was revealed to protect UVB-induced erythema formation using guinea pigs in preliminary in vivo study. The flowers of P. persica extract have been suggested to be beneficial for protecting UV-induced skin damage when topically applied.

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