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MUCUNA PRURIENS DECREASES SEXUAL ACTIVITY IN FEMALE RATS.

Abstract no :  2-1&2-DG-041
Author(s) :  Rajendran V, Joseph T, David J.,
Address :  Department of Pharmacology, St. Joh’s Medical College, Bangalore -560034,
Source :  Indian Drugs 1997, 43(3), 136-9.
Title :  MUCUNA PRURIENS DECREASES SEXUAL ACTIVITY IN FEMALE RATS.
Abstract :      Mucuna pruriens (MP) (Kapikcchu) seed powder 3g. containing 100 mg L-dopa (LD) showed a more significant inhibitory effect than 100 mg LD on sexual behaviour in sexually receptive female rats.  The females showed rejection and exhibited decreased lordosis when males attempted to mount. The index of rejections indicated as a significant decrease in lordosis quotient with a corresponding increase in rejection quoteint.  The same animals on treatment with water a week earlier or later accepted the male without any rejection.  The results indicate that while both LD & MP inhibited sexual behaviour in females, the inhibitory effect of MP was more than that of LD indicating the presence of other constitutent in MP contributing to this effect.

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