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EVIDENCE FOR FREE RADICAL SCAVENGING ACTIVITY OF ASHWAGANDHA ROOT POWDER IN MICE

Abstract no :  2-1&2-DG-052
Author(s) :  Sunand Panda and Anand Kar,
Address :  School  of  Life Sciences, D.A. University,  Vigyan  Bhavan, Khandwa Road, Indore - 452001, India,
Source :  IndianJournalof Physiology and Pharmacology 1997; 41(4): pp. 424-426.
Title :  EVIDENCE FOR FREE RADICAL SCAVENGING ACTIVITY OF ASHWAGANDHA ROOT POWDER IN MICE
Abstract :      The  effects  of ASVAGANDHA root powder (0.7 and  1.4  g/kg b.w./day)  administered for 15 days and 30 days was  investigated on  lipid  perioxidation (LPO), superoxide  dismutase  (SOD)  and catalase  (CAT) activities in mice. While 15 days treatment  with ASVAGANDHA  root powder did not produce any significant  change, 30  days treatment produced a significant decrase in LPO, and  an increasa  in  both  SOD  and CAT.  Our  findingas  indicate  that ASVAGANDHA   root  powder  possesses  free  radical   scavenging activity,  which  may  be  responsible  for  its  pharmacological effects.

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