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ISOLATION OF A POTENT MOSQUITO REPELLENT FROM VITEX NEGUNDO L. AN ALTERNATIVE SOURCE OF ROTUNDIAL

Abstract no :  3-1...4-SV-366
Author(s) :   (Research and Development Centre, E.I.D parry (India) Ltd., 145, Devanahalli Road, Bangalore 560 049 Karnataka, India)
Address :  Amancharla, P.K.; Muthuraj, P.S.; Rao, G.V.; Singh, O.V.
Source :   Natural Product Sciences, v. 5(2):p. 104-106, 1999
Title :  ISOLATION OF A POTENT MOSQUITO REPELLENT FROM VITEX NEGUNDO L.  AN ALTERNATIVE SOURCE OF ROTUNDIAL
Abstract :      The chloroform fraction of the aqueous extract of the fresh leaves of Vitex negundo (NIRGUNDI) by bio-activity guided isolation yielded a pure compound, Rotundial (C9H1202) which has shown potent mosquito repellent activity. Using spectral data (UV, IR, IH & 13C NMR  and MS) its structure has been elucidated. Rotundial showed 94.1 % repellency up to 4th hour and maintained 82 % at 6th hour at application dose of 0.15 mg/sq. cm.

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