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CITRAL: A CYTOTOXIC PRINCIPLE ISOLATED FROM THE ESSENTIAL OIL OF CYMBOPOGON CITRATUS AGAINST P388 LEUKAEMIA CELLS.

Abstract no :  2-1&2-DG-114
Author(s) :  Dubey, N.K.; Takeya, K.; Itokawa, H.
Address :  Department of Botany, Banaras Hindu University, Varanasi 221 005, India
Source :  Current Sciences, v. 73(1): p. 22-24, 1997.
Title :  CITRAL: A CYTOTOXIC  PRINCIPLE ISOLATED FROM THE ESSENTIAL OIL OF CYMBOPOGON CITRATUS AGAINST P388 LEUKAEMIA CELLS.
Abstract :      Cymbopogon citratus (BHUSTRINA) is described as pungent, bitter, sharp and hot in Ayurveda.  It is used in fever, vomiting and rheumatism.  The essential oil obtained from C. citratus  and its isolated principle viz., citral have been tested for cytotoxicity against   p388 leukaemia cells.  The cytotoxicity of citral, IC50 against p388 mouse leukaemic cells was 71 micro g/ml. This is the first report on cytotoxicity of citral and indicates its possible exploitation as a pesticidal and chemotherapeutic agent.

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